{"id":8524,"date":"2025-10-20T18:10:11","date_gmt":"2025-10-20T18:10:11","guid":{"rendered":"https:\/\/healthmedicinet.com\/review\/hmn-differences-similarities-and-which-is-better-for-you-in-2025-38\/"},"modified":"2025-12-23T14:23:15","modified_gmt":"2025-12-23T14:23:15","slug":"hmn-trulicity-dulaglutide-and-victoza-differences-similarities-and-which-is-better-for-you-in-2025","status":"publish","type":"post","link":"https:\/\/healthmedicinet.com\/review\/hmn-trulicity-dulaglutide-and-victoza-differences-similarities-and-which-is-better-for-you-in-2025\/","title":{"rendered":"HMN: Trulicity (dulaglutide) and Victoza Differences, similarities, and which is better for you in 2025"},"content":{"rendered":"<p>\n<br \/>Do you know:  Differences, similarities, and which is better for you in 2025<\/p>\n<div id=\"main-content\">\n<div id=\"post-intro\">\n<div id=\"takeaways\">\n<h2>Key takeaways<\/h2>\n<ul>\n<li>\n<p>Trulicity (dulaglutide) and Victoza (liraglutide) are injectable glucagon-like peptide-1 receptor agonists used in the treatment of Type 2 diabetes, with Trulicity administered weekly and Victoza daily.<\/p>\n<\/li>\n<li>\n<p>Both medications are effective in lowering blood sugar levels and reducing cardiovascular events in Type 2 diabetes patients, with no significant difference in their efficacy or safety profiles.<\/p>\n<\/li>\n<li>\n<p>Common side effects include gastrointestinal issues such as nausea and diarrhea, and both medications require caution in patients with a history of pancreatitis or renal impairment.<\/p>\n<\/li>\n<li>\n<p>The choice between Trulicity and Victoza may depend on patient preference for once-weekly versus once-daily injections, as well as individual insurance coverage and cost considerations.<\/p>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<p><a href=\"#drug-overview-differences\">Drug overview &amp; main differences<\/a> | <a href=\"#conditions-treated\">Conditions treated<\/a> | <a href=\"#efficacy\">Efficacy<\/a> | <a href=\"#insurance-coverage-cost-comparison\">Insurance coverage and cost comparison<\/a> | <a href=\"#side-effects\">Side effects<\/a> | <a href=\"#drug-interactions\">Drug interactions<\/a> | <a href=\"#warnings\">Warnings<\/a> | <a href=\"#FAQ\">FAQ<\/a><\/p>\n<p><span style=\"font-weight: 400;\">Trulicity and Victoza are two prescription injectable drugs indicated in the treatment of Type 2 diabetes mellitus (T2DM). In the United States, approximately 1 in 10 people have a form of<\/span><a href=\"https:\/\/www.cdc.gov\/diabetes\/basics\/type2.html\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\"> diabetes<\/span><\/a><span style=\"font-weight: 400;\">, and it is estimated that 90% of those are <\/span><span style=\"font-weight: 400;\">Type 2 diabetes<\/span><span style=\"font-weight: 400;\">. People with Type 1 diabetes are unable to produce insulin, a hormone needed to maintain blood sugar balance in their cells for energy. Type 2 diabetics are able to produce insulin, but their body doesn\u2019t respond to it appropriately. This allows blood sugar levels to get too high. There are serious health consequences associated with high blood sugar including heart disease, kidney disease, and vision loss.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Trulicity (dulaglutide) and Victoza (liraglutide) belong to a class of medications known as glucagon-like peptide-1 receptor agonists, often referred to as <\/span><span style=\"font-weight: 400;\">GLP-1s<\/span><span style=\"font-weight: 400;\">. This is a relatively new class of medications in the treatment of Type 2 diabetes. Other options in this class include <\/span><span style=\"font-weight: 400;\">Bydureon<\/span><span style=\"font-weight: 400;\"> (exenatide), <\/span><span style=\"font-weight: 400;\">Byetta<\/span><span style=\"font-weight: 400;\"> (exenatide), and <\/span><span style=\"font-weight: 400;\">Ozempic<\/span><span style=\"font-weight: 400;\"> (semaglutide). For the purposes of this review, we will specifically compare Trulicity and Victoza<\/span><\/p>\n<h2 id=\"drug-overview-differences\">What are the main differences between Trulicity vs. Victoza<\/h2>\n<p><span style=\"font-weight: 400;\">Trulicity<\/span><span style=\"font-weight: 400;\"> (dulaglutide) is a glucagon-like peptide-1 receptor agonist. It is a once-weekly injectable subcutaneous drug produced by Eli Lilly available only by prescription. GLP-1s work by mimicking the structure of naturally occurring hormones in the human body known as incretin hormones. When you eat food, your stomach releases these hormones, and they, in turn, stimulate the release of insulin from the pancreas. Insulin helps control blood sugar levels by helping cells absorb glucose to be used for energy. T2DM patients often lack enough incretin hormones to stimulate this process, and that is why the GLP-1 receptor agonists are effective at helping them manage their blood sugar. Trulicity is available in 4 different doses: 0.75 mg\/0.5 ml, 1.5 mg\/0.5 ml, 3 mg\/0.5 ml, and 4.5 mg\/0.5 ml. Trulicity is provided in single-use injection pens and is intended for once-weekly injections only.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Victoza<\/span><span style=\"font-weight: 400;\"> (liraglutide) is a once-daily GLP-1 agonist produced by Novo Nordisk which is also a subcutaneous injectable and available by prescription only. Both Trulicity and Victoza are considered long-acting GLP-1 agonists, but the biggest difference is that Trulicity is given once weekly and Victoza is given once daily. Victoza is available in 18 mg\/3 ml pens that can be used to administer 3 different doses: 0.6 mg, 1.2 mg, and 1.8 mg.<\/span><\/p>\n<table class=\"singlecare-table\">\n<thead>\n<tr>\n<th><span class=\"title\">Main differences between Trulicity and Victoza<\/span><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><b>Drug class<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Glucagon-like peptide-1 receptor agonist (GLP-1 RA)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Glucagon-like peptide-1 receptor agonist (GLP-1 RA)<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Brand\/generic status<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Brand only<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Brand only<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>What is the generic name?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">dulaglutide<\/span><\/td>\n<td><span style=\"font-weight: 400;\">liraglutide<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>What form(s) does the drug come in?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Once-weekly single-use injection pens<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Once-daily multi-dose injection pens<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>What is the standard dosage?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">1.5 mg once weekly<\/span><\/td>\n<td><span style=\"font-weight: 400;\">1.8 mg once daily<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>How long is the typical treatment?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Long term<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Long term<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Who typically uses the medication?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Adults<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Children and adolescents age 10 and up, adults<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 id=\"conditions-treated\">Conditions treated by Trulicity and Victoza<\/h2>\n<p><span style=\"font-weight: 400;\">Trulicity and Victoza are both indicated in the treatment of Type 2 diabetes mellitus. They each also carry an additional indication for reducing cardiovascular events and cardiovascular mortality in patients who have Type 2 diabetes mellitus. This includes stroke and myocardial infarction. The active ingredient in Victoza, liraglutide, is also marketed under the brand name <\/span><span style=\"font-weight: 400;\">Saxenda<\/span><span style=\"font-weight: 400;\"> which is approved by Food and Drug Administration (FDA) for weight loss as a component in the treatment of obesity.<\/span><\/p>\n<table class=\" singlecare-table\">\n<tbody>\n<tr>\n<td><span style=\"font-weight: 400;\">Type 2 diabetes mellitus<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Reduction of cardiovascular mortality<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 id=\"efficacy\">Is Ozempic or Victoza more effective?<\/h2>\n<p><span style=\"font-weight: 400;\">The <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25018121\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">AWARD-6<\/span><\/a><span style=\"font-weight: 400;\"> trial was a randomized clinical trial comparing Trulicity and Victoza. The results concluded that both were relatively equal in lowering hemoglobin A1C (HbA1C), a lab value that is indicative of long-term blood glucose levels. Both were also similarly safe and tolerable. The decision to choose one over the other may come down to preference of once weekly or once-daily injections. Only your physician can decide what is best for you.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">A <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31422062\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">meta-analysis<\/span><\/a><span style=\"font-weight: 400;\"> of clinical studies also compared cardiovascular outcomes of Trulicity and Victoza as well as other GLP-1 agonists. The analysis found that GLP-1 agonists reduced cardiovascular events like heart attack by 12% overall. There was no statistical difference in the amount decreased by Trulicity, Victoza, or other GLP-1 agonists.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Both Trulicity and Victoza show effectiveness in the treatment of diabetes and the reduction of cardiovascular events. This is not intended to be medical advice. Talk to your endocrinology specialist to determine which may be best for you.<\/span><\/p>\n<h2 id=\"insurance-coverage-cost-comparison\">Coverage and cost comparison of Trulicity vs. Victoza<\/h2>\n<p><span style=\"font-weight: 400;\">Trulicity is a prescription medication covered by most Medicare and commercial insurance providers. Some insurance companies may prefer one GLP-1 agonist over another. Your pharmacist can help you determine if that is the case. The out-of-pocket cost for Trulicity can be almost $1,300.  helps you save hundreds of dollars on prescription Trulicity. A  <\/span><span style=\"font-weight: 400;\">savings card<\/span><span style=\"font-weight: 400;\"> lowers the cost of Trulicity to approximately $774.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Victoza is a prescription medication covered by most Medicare and commercial insurance plans. Without insurance, Victoza can cost up to $1,330. A  <\/span><span style=\"font-weight: 400;\">savings card<\/span><span style=\"font-weight: 400;\"> lowers this price to around $900.<\/span><\/p>\n<table class=\" singlecare-table\">\n<tbody>\n<tr>\n<td><b>Typically covered by insurance?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Typically covered by Medicare Part D?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Quantity<\/b><\/td>\n<td><span style=\"font-weight: 400;\">4, 1.5 mg\/0.5 ml pens<\/span><\/td>\n<td><span style=\"font-weight: 400;\">3, 18mg\/ 3ml pens<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Typical Medicare copay<\/b><\/td>\n<td><span style=\"font-weight: 400;\">$0-$1000<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$0-$1100<\/span><\/td>\n<\/tr>\n<tr>\n<td><b> cost<\/b><\/td>\n<td><span style=\"font-weight: 400;\">$774-$867<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$898-$1100<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 id=\"side-effects\">Common side effects of Trulicity vs. Victoza<\/h2>\n<p><span style=\"font-weight: 400;\">The most common side effects of GLP-1 agonists are related to the gastrointestinal system, and they include nausea, diarrhea, and vomiting. The prescribing information for <\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=463050bd-2b1c-40f5-b3c3-0a04bb433309\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Trulicity<\/span><\/a><span style=\"font-weight: 400;\"> and <\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=5a9ef4ea-c76a-4d34-a604-27c5b505f5a4\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Victoza<\/span><\/a><span style=\"font-weight: 400;\"> both report that approximately 20% of treated patients will experience nausea and roughly 12% will experience diarrhea. Decreased appetite will occur in about 9% of patients treated with either drug. Due to these side effects, it is not uncommon for patients to experience <\/span><span style=\"font-weight: 400;\">weight loss<\/span><span style=\"font-weight: 400;\"> when taking either Trulicity or Victoza. Gastrointestinal side effects increase with dosage. Many prescribers will start you at a lower dose and titrate you up slowly to minimize the onset of these side effects.<\/span><\/p>\n<table class=\" singlecare-table\">\n<tbody>\n<tr>\n<td><b>Side Effect<\/b><\/td>\n<td><b>Applicable?<\/b><\/td>\n<td><b>Frequency<\/b><\/td>\n<td><b>Applicable?<\/b><\/td>\n<td><b>Frequency<\/b><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Nausea<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">21.1%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">20%<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Diarrhea<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">12.6%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">12%<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Vomiting<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">12.7%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">9%<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Abdominal pain<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">9.4%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">No<\/span><\/td>\n<td><span style=\"font-weight: 400;\">n\/a<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Decreased appetite<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">8.6%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">9%<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Dyspepsia<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">5.8%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">7%<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Fatigue<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">5.6%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">No<\/span><\/td>\n<td><span style=\"font-weight: 400;\">n\/a<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Headache<\/span><\/td>\n<td><span style=\"font-weight: 400;\">No<\/span><\/td>\n<td><span style=\"font-weight: 400;\">n\/a<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">10%<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Constipation<\/span><\/td>\n<td><span style=\"font-weight: 400;\">No<\/span><\/td>\n<td><span style=\"font-weight: 400;\">n\/a<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">5%<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Back pain<\/span><\/td>\n<td><span style=\"font-weight: 400;\">No<\/span><\/td>\n<td><span style=\"font-weight: 400;\">n\/a<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">5%<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><span style=\"font-weight: 400;\">Source: Trulicity <\/span><span style=\"font-weight: 400;\">(<\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=463050bd-2b1c-40f5-b3c3-0a04bb433309\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">DailyMed<\/span><\/a><span style=\"font-weight: 400;\">)<\/span><span style=\"font-weight: 400;\"> Victoza <\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=5a9ef4ea-c76a-4d34-a604-27c5b505f5a4\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">(DailyMed<\/span><\/a><span style=\"font-weight: 400;\">)<\/span><\/p>\n<h2 id=\"drug-interactions\">Drug interactions of Trulicity vs. Victoza<\/h2>\n<p><span style=\"font-weight: 400;\">Trulicity and Victoza delay gastric emptying and therefore may alter the rate of absorption of oral drugs administered with them. This is especially true for narrow therapeutic index drugs like Coumadin (warfarin) and Synthroid (levothyroxine). This effect is more pronounced at higher doses.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The risk of serious side effects such as hypoglycemia, or low blood sugar, increases with Trulicity and Victoza when taken with other antidiabetic medications. Your endocrinologist may decrease your doses of oral medications like metformin or your insulin before starting GLP-1 receptor agonists.\u00a0<\/span><\/p>\n<table class=\" singlecare-table\">\n<tbody>\n<tr>\n<td><span style=\"font-weight: 400;\">Benazepril<\/span><br \/><span style=\"font-weight: 400;\">Captopril<\/span><br \/><span style=\"font-weight: 400;\">Enalapril<\/span><br \/><span style=\"font-weight: 400;\">Lisinopril<\/span><br \/><span style=\"font-weight: 400;\">Quinapril<\/span><br \/><span style=\"font-weight: 400;\">Ramipril<\/span><\/td>\n<td><span style=\"font-weight: 400;\">ACE Inhibitors<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Azilsartan<\/span><br \/><span style=\"font-weight: 400;\">Candesartan<\/span><br \/><span style=\"font-weight: 400;\">Eprosartan<\/span><br \/><span style=\"font-weight: 400;\">Irbesartan<\/span><br \/><span style=\"font-weight: 400;\">Losartan<\/span><br \/><span style=\"font-weight: 400;\">Olmesartan<\/span><br \/><span style=\"font-weight: 400;\">Valsartan<\/span><br \/><span style=\"font-weight: 400;\">Telmisartan<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Angiotensin II receptor blockers<\/span><br \/><span style=\"font-weight: 400;\"> (ARBs)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Clarithromycin<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Antibiotic<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Aspirin<\/span><br \/><span style=\"font-weight: 400;\">Bismuth salicylate<\/span><br \/><span style=\"font-weight: 400;\">Magnesium salicylate<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Salicylates<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Levothyroxine<\/span><br \/><span style=\"font-weight: 400;\">Liothyronine<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Thyroid replacements<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Estrogen<\/span><br \/><span style=\"font-weight: 400;\">Progesterone<\/span><br \/><span style=\"font-weight: 400;\">Testosterone<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Hormones<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 id=\"warnings\">Warnings of Trulicity and Victoza<\/h2>\n<p><span style=\"font-weight: 400;\">Do not use Trulicity or Victoza if you have had a history of allergic reactions or hypersensitivity reactions to any GLP-1 receptor agonists. Localized injection site reactions may occur.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Trulicity and Victoza have been linked to thyroid C-cell tumors (adenomas or carcinomas) that were dose and treatment-duration dependent in lab animals. It is unknown if this can happen in humans. Routine monitoring of the thyroid and serum calcitonin is recommended for the detection of thyroid tumors and thyroid cancer.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Pancreatitis<\/span><span style=\"font-weight: 400;\"> has been reported in patients taking Trulicity and Victoza. Patients should monitor for signs of pancreatitis including severe abdominal pain which may radiate to the back. Vomiting may also accompany these symptoms.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">While Trulicity and Victoza are diabetes medications used to treat hyperglycemia, high blood glucose levels, they may cause hypoglycemia once initiated. This risk is increased with the concurrent use of insulin and oral antidiabetic agents such as <\/span><span style=\"font-weight: 400;\">sulfonylureas<\/span><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Renal function should be monitored in patients taking GLP-1 receptor agonists. Trulicity or Victoza may cause acute renal failure or worsening of chronic kidney problems. Doses may need to be adjusted or the medication may need to be stopped if it worsens.<\/span><\/p>\n<h2 id=\"FAQ\">Frequently asked questions about Trulicity vs. Victoza<\/h2>\n<h3><span style=\"font-weight: 400;\">What is Trulicity?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Trulicity is a prescription drug classified as a glucagon-1 peptide-like receptor agonist that is indicated in the treatment of Type 2 diabetes mellitus. Trulicity is a once-weekly injection available in single-use pens in dosages of 0.75 mg, 1.5 mg, 3 mg, and 4.5 mg.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">What is Victoza?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Victoza is a prescription medication belonging to a class known as glucagon-1 peptide-like receptor agonist that is indicated in the treatment of Type 2 diabetes mellitus. Victoza is a once-daily injection available in multi-dose pens which are capable of administering three approved doses: 0.6 mg, 1.2 mg, and 1.8 mg.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Are Trulicity and Victoza the same?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">While Trulicity and Victoza are both glucagon-1 peptide-like receptor agonists, they are not the same medication. Trulicity contains the active ingredient dulaglutide and is once weekly. Victoza contains liraglutide and is once daily.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Is Trulicity or Victoza better?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Trulicity and Victoza have clinically similar outcomes related to the treatment of Type 2 diabetes mellitus and reducing cardiovascular events in Type 2 diabetes mellitus patients. Their safety and tolerability profiles are also similar. Trulicity has the advantage of being only once-weekly, while Victoza is once daily. This may be a factor when your healthcare professional determines which one is right for you.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Can I use Trulicity or Victoza while pregnant?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Adequate studies on the safety of the diabetes drugs Trulicity and Victoza have not been completed with regard to pregnancy and breastfeeding. Your doctor must weigh the potential risks and benefits. There are other proven therapies to treat diabetes in pregnancy, including insulin, which would be preferred.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Can I use Trulicity or Victoza with alcohol?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Alcohol consumption should be limited by anyone with Type 2 diabetes as it affects blood sugar and kidney and liver function. Talk to your physician if you drink regularly before starting Trulicity or Victoza.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">What is a good substitute for Victoza?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Victoza may not be the best choice for you if you struggle with daily injections or your insurance company doesn\u2019t prefer it. Check to see if you have better coverage for once-weekly GLP-1 agonists such as Trulicity, Bydureon, or Ozempic.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Is Trulicity cheaper than Victoza?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">The out-of-pocket costs for Trulicty and Victoza are similar and upwards of $1300 per month. With a  <\/span><span style=\"font-weight: 400;\">discount card<\/span><span style=\"font-weight: 400;\">, Trulicity is slightly cheaper than the cost of Victoza but you can save hundreds of dollars or both prescriptions versus retail prices.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Is Victoza hard on kidneys?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Victoza can worsen pre-existing chronic renal failure. It can even induce acute renal failure. 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<\/g>\n<\/svg>\t\t\t\t\t\t\t\t<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Do you know: Differences, similarities, and which is better for you in 2025 Key takeaways Trulicity (dulaglutide) and Victoza (liraglutide) are injectable glucagon-like peptide-1 receptor agonists used in the treatment of Type 2 diabetes, with Trulicity administered weekly and Victoza daily. Both medications are effective in lowering blood sugar levels and reducing cardiovascular events in [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-8524","post","type-post","status-publish","format-standard","hentry","category-health-news"],"blocksy_meta":[],"_links":{"self":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts\/8524","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/comments?post=8524"}],"version-history":[{"count":1,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts\/8524\/revisions"}],"predecessor-version":[{"id":8843,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts\/8524\/revisions\/8843"}],"wp:attachment":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/media?parent=8524"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/categories?post=8524"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/tags?post=8524"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}