{"id":8743,"date":"2025-12-10T05:45:04","date_gmt":"2025-12-10T05:45:04","guid":{"rendered":"https:\/\/healthmedicinet.com\/review\/hmn-what-are-the-main-side-effects-of-meloxicam-in-2025\/"},"modified":"2025-12-10T05:45:04","modified_gmt":"2025-12-10T05:45:04","slug":"hmn-what-are-the-main-side-effects-of-meloxicam-in-2025","status":"publish","type":"post","link":"https:\/\/healthmedicinet.com\/review\/hmn-what-are-the-main-side-effects-of-meloxicam-in-2025\/","title":{"rendered":"HMN: What are the main side effects of meloxicam? in 2025"},"content":{"rendered":"<p>\n<br \/>Do you know:  What are the main side effects of meloxicam? in 2025<\/p>\n<div id=\"main-content\">\n<div id=\"post-intro\">\n<div id=\"takeaways\">\n<h2>Key takeaways<\/h2>\n<ul>\n<li>\n<p><span style=\"font-weight: 400;\">Meloxicam is a nonsteroidal anti-inflammatory drug that is prescribed for arthritis conditions, as an alternative to over-the-counter products like Advil, Aleve, and aspirin.<\/span><\/p>\n<\/li>\n<li>\n<p><span style=\"font-weight: 400;\">Side effects of meloxicam often involve the gastrointestinal tract, ranging from simple nausea to serious bleeding ulcers; kidneys, such as fluid retention and kidney failure; and cardiovascular system, including high blood pressure and heart attacks.<\/span><\/p>\n<\/li>\n<li>\n<p><span style=\"font-weight: 400;\">Interactions with other drugs and health conditions are a major concern with meloxicam as they can heighten the risk of adverse effects.<\/span><\/p>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<section class=\"table-of-contents\">\n<div class=\"anchorLinks\">\n<div class=\"mobile-only\">\n<div class=\"dropdownLists\">\n<div tabindex=\"0\" class=\"dropdownBtn\"><span class=\"listsIcon\"><br \/>\n\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.singlecare.com\/blog\/wp-content\/themes\/singlecare\/images\/union.svg\" width=\"14\" height=\"20\"\/><\/span><br \/>\n\t\t\t\t\t\t\t<label><\/label><br \/>\n\t\t\t\t\t\t\t<span class=\"downArrow\"><br \/>\n\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.singlecare.com\/blog\/wp-content\/themes\/singlecare\/images\/dropDownArrow.svg\" width=\"24\" height=\"24\"\/><br \/>\n\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t<\/div>\n<\/p><\/div>\n<\/p><\/div>\n<\/p><\/div>\n<\/section>\n<p>\u00a0<\/p>\n<p><iframe loading=\"lazy\" title=\"Arthritis treatment: What is meloxicam?\" width=\"1290\" height=\"726\" src=\"https:\/\/www.youtube.com\/embed\/UqZWh5Fqh3c?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe><\/p>\n<p><span style=\"font-weight: 400;\">Meloxicam<\/span><span style=\"font-weight: 400;\"> is a generic prescription drug that relieves pain and swelling caused by osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis. Formerly known by the brand names Mobic, Vivlodex, and Anjeso, meloxicam can be taken by mouth as a tablet, capsule, disintegrating tablet, or oral suspension, or the brand-name version Xifyrm can be injected directly into the bloodstream by a healthcare professional.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">As a <\/span><span style=\"font-weight: 400;\">nonsteroidal anti-inflammatory drug (NSAID)<\/span><span style=\"font-weight: 400;\">, meloxicam belongs to the same family as the well-known drugs aspirin, ibuprofen, and naproxen. However, meloxicam is not necessarily an amped-up version of Advil or Aleve; how well an individual NSAID works is dependent on both dose and an individual\u2019s responsiveness to one medicine versus another. People should be aware that meloxicam comes with serious risks, side effects, warnings, and drug interactions, which also pertain to over-the-counter (OTC) NSAIDs as well.\u00a0<\/span><\/p>\n<p><b> <\/b><b>Learn more about meloxicam<\/b><b> | <\/b><b>Get meloxicam discounts<\/b><\/p>\n<h2 id=\"common-side-effects-of-meloxicam\"><span style=\"font-weight: 400;\">Common side effects of meloxicam<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The most common side effects of meloxicam (affecting <\/span><a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2016\/020938s024s025,021530s014s015lbl.pdf\"><span style=\"font-weight: 400;\">2% or more<\/span><\/a><span style=\"font-weight: 400;\"> of people taking the medication) are:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Abdominal pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Headache<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Flu-like symptoms<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dizziness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nausea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diarrhea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sore throat\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fluid retention<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Accidents and falls<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Constipation<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Insomnia<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Upper respiratory tract infection<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Urinary tract infection<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Joint pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Back pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Stomach upset<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Flatulence<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Rash<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Itching<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Urination problems<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Vomiting<\/span><\/li>\n<\/ul>\n<h2 id=\"serious-side-effects-of-meloxicam\"><span style=\"font-weight: 400;\">Serious side effects of meloxicam<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Meloxicam can produce serious and even life-threatening side effects, particularly if used in high doses or for an extended time. These include<\/span><span style=\"font-weight: 400;\">:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Heart attack<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Stroke<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Blood clots<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">High blood pressure<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Congestive heart failure<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Bleeding, ulcers, or perforations in the stomach or intestine<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Liver damage or liver failure<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Kidney dysfunction or kidney failure<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Anemia<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Bleeding problems<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Asthma attacks in people with asthma<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Severe and <\/span><a href=\"https:\/\/online.lexi.com\/lco\/medguides\/615074.pdf\"><span style=\"font-weight: 400;\">potentially life-threatening<\/span><\/a><span style=\"font-weight: 400;\"> allergic reactions such as anaphylaxis, trouble breathing, or severe skin reactions<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Serious side effects will require immediate medical attention.<\/span><\/p>\n<h3 id=\"meloxicam-and-headaches\"><span style=\"font-weight: 400;\">Meloxicam and headaches<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Headaches are a common, less serious side effect of meloxicam. In two 12-week clinical trials in patients with osteoarthritis or rheumatoid arthritis, between 5.5% to 8.3% of people taking meloxicam reported headaches. Calling into question whether meloxicam was the cause of the headaches, those 12-week trials also found that patients taking inactive placebo tablets had similar or higher rates of headaches than those taking meloxicam. <\/span><a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2016\/020938s024s025,021530s014s015lbl.pdf\"><span style=\"font-weight: 400;\">In a six-month trial<\/span><\/a><span style=\"font-weight: 400;\">, 2.6% to 3.6% of people taking meloxicam experienced headaches, and the potential side effect was not dose-dependent.<\/span><\/p>\n<h3 id=\"meloxicam-and-weight-gain\"><span style=\"font-weight: 400;\">Meloxicam and weight gain<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Based on weight side effects seen with anti-inflammatory steroids, people often ask, \u201cDoes meloxicam cause weight gain?\u201d Weight gain and loss are uncommon side effects of meloxicam, observed in less than 2% of people taking it. However, fluid retention (edema) is a common side effect, reported in 0.6% to 4.5% of people taking meloxicam in <\/span><a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2016\/020938s024s025,021530s014s015lbl.pdf\"><span style=\"font-weight: 400;\">clinical studies<\/span><\/a><span style=\"font-weight: 400;\">. Left untreated, edema can lead to cardiovascular problems including congestive heart failure in vulnerable people. Fluid retention can be partly identified by an unexplained rise in body weight, so involuntary weight gain should be reported to the prescribing physician or other healthcare professional.\u00a0<\/span><\/p>\n<h3 id=\"meloxicam-overdose\"><span style=\"font-weight: 400;\">Meloxicam overdose<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">As an NSAID, a meloxicam overdose can lead to serious health issues, evident from <\/span><a href=\"https:\/\/link.springer.com\/article\/10.2165\/00002018-199005040-00003\"><span style=\"font-weight: 400;\">more common experience<\/span><\/a><span style=\"font-weight: 400;\"> of people overdosing on common over-the-counter NSAIDs, such as aspirin or ibuprofen. The most common symptoms of an NSAID overdose are:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Lack of energy<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Drowsiness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nausea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Vomiting<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Stomach pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Blurred vision<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dizziness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Bloody vomiting<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Black or tarry stools<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">A severe overdose can result in high blood pressure, kidney failure, seizures, coma, respiratory distress, and death. People with any symptoms of NSAID overdose will require immediate medical attention.<\/span><\/p>\n<h2 id=\"how-long-do-meloxicam-side-effects-last\"><span style=\"font-weight: 400;\">How long do meloxicam side effects last?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Most of the common side effects of meloxicam are temporary and will abate after the drug is discontinued. Unfortunately, meloxicam <\/span><a href=\"https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/Meloxicam#section=Metabolism-Metabolites\"><span style=\"font-weight: 400;\">stays in the body much longer<\/span><\/a><span style=\"font-weight: 400;\"> than other NSAIDs, so side effects may linger a few days after the last dose. More serious side effects, such as ulcers and gastrointestinal bleeding, can take much longer to resolve, even after discontinuing meloxicam.<\/span><\/p>\n<h2 id=\"meloxicam-warnings-contraindications\"><span style=\"font-weight: 400;\">Meloxicam warnings &amp; contraindications<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Like all prescription NSAIDs, meloxicam has risks that may outweigh the benefits for some people. The Food and Drug Administration (FDA) determines if a medicine is safe for certain people by issuing contraindications and warnings. When a medicine carries a high risk for hazardous adverse effects in certain people, it is <\/span><b>contraindicated<\/b><span style=\"font-weight: 400;\"> for those people\u2014it is<\/span><i><span style=\"font-weight: 400;\"> never<\/span><\/i><span style=\"font-weight: 400;\"> to be used in those patients. When a medication is riskier than normal in some patients, the medication comes with a <\/span><b>warning.<\/b><span style=\"font-weight: 400;\"> It may be okay to take the medicine, but use and dosage will require monitoring or modification.\u00a0<\/span><\/p>\n<h3 id=\"allergies\"><span style=\"font-weight: 400;\">Allergies<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Meloxicam should never be used in people with known allergies to meloxicam or other NSAIDs.<\/span><\/p>\n<h3 id=\"coronary-artery-bypass-graft-cabg-surgery\"><span style=\"font-weight: 400;\">Coronary artery bypass graft (CABG) surgery<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Better known as \u201cbypass surgery\u201d or \u201ccoronary bypass,\u201d CABG surgery restores normal blood flow to the heart\u2019s muscles by either diverting a coronary artery or using a blood vessel graft to \u201cgo around\u201d an obstructed coronary artery. Because meloxicam can cause blood clotting and cardiovascular problems, it is never used in the period leading up to bypass surgery or in the weeks after.<\/span><\/p>\n<h3 id=\"asthma\"><span style=\"font-weight: 400;\">Asthma<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Some people have aspirin-sensitive asthma, also known as <\/span><a href=\"https:\/\/www.aaaai.org\/tools-for-the-public\/conditions-library\/asthma\/aspirin-exacerbated-respiratory-disease-(aerd)\"><span style=\"font-weight: 400;\">aspirin-exacerbated respiratory disease (AERD)<\/span><\/a><span style=\"font-weight: 400;\">. When given aspirin or other NSAIDs, those with AERD react with classic asthma symptoms, such as wheezing and coughing. This reaction can be fatal. Meloxicam should never be given to people with aspirin-sensitive asthma. Other people with asthma will require caution and monitoring just in case there is a serious reaction.<\/span><\/p>\n<h3 id=\"other-medical-conditions\"><span style=\"font-weight: 400;\">Other medical conditions<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Meloxicam and other NSAIDs may worsen existing medical conditions, so these medications may be avoided or require caution and monitoring when prescribed to people with risk factors such as:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Heart disease<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Congestive heart failure<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Blood clots and stroke<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Ulcers or bleeding in the digestive system<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">High blood pressure<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fluid retention<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Bleeding disorders<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Kidney problems<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Liver disease<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Poor general health<\/span><\/li>\n<\/ul>\n<h3 id=\"children\"><span style=\"font-weight: 400;\">Children<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Meloxicam is FDA-approved to treat juvenile rheumatoid arthritis in children 2 years of age and older. In three clinical trials, children experienced the same types of side effects as adults, but at a higher rate.<\/span><\/p>\n<h3 id=\"seniors\"><span style=\"font-weight: 400;\">Seniors<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">People 65 years and older are at a higher risk for side effects, so they may be started at a lower dose and monitored.\u00a0<\/span><\/p>\n<h3 id=\"fertility\"><span style=\"font-weight: 400;\">Fertility<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Meloxicam, like other NSAIDs, may cause a delay in ovulation, so women who are trying to get pregnant or undergoing fertility treatment may not be prescribed meloxicam.<\/span><\/p>\n<h3 id=\"pregnancy\"><span style=\"font-weight: 400;\">Pregnancy<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Meloxicam is not to be taken by pregnant women after 30 weeks because NSAIDs affect the heart development in the unborn baby. There is not enough research to know if meloxicam is safe for women or an unborn baby in the first 30 weeks of pregnancy. Women who are pregnant or considering getting pregnant should discuss the risks with a doctor.\u00a0<\/span><\/p>\n<h3 id=\"breastfeeding\"><span style=\"font-weight: 400;\">Breastfeeding<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">It is not certain if meloxicam is safe to take while nursing or how much passes into human breast milk. Nursing mothers should seek medical advice before taking meloxicam.<\/span><\/p>\n<h3 id=\"dependence\"><span style=\"font-weight: 400;\">Dependence<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Meloxicam does not create dependence nor does it require a tapered dose when stopping the medication.\u00a0<\/span><\/p>\n<div id=\"coupon-cta\" class=\"coupon-cta master-template\">\n<p id=\"headline\">Save up to 80% on Meloxicam with <\/p>\n<p id=\"subheadline\">Different pharmacies offer different prices for the same medication.  helps find the best price for you.<\/p>\n<div class=\"details-wrap\">\n<p>\n\t\t\t\t\tMeloxicam 15 mg (30 Tablets)\t\t\t\t<\/p>\n<p>\n\t\t\t\t\t23666 &#8211; Hampton, VA\t\t\t\t<\/p>\n<\/p><\/div>\n<div class=\"api-response\">\n<div class=\"coupon\">\n<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-kroger.svg\" alt=\"Kroger Pharmacy\"\/>\t\t\t<\/div>\n<\/p><\/div>\n<div class=\"coupon\">\n<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-harristeeter.svg\" alt=\"Harris Teeter Pharmacy\"\/>\t\t\t<\/div>\n<\/p><\/div>\n<\/p><\/div>\n<p>\t\t\tSee Meloxicam prices at all pharmacies\n\t\t<\/p><\/div>\n<h2 id=\"meloxicam-interactions\"><span style=\"font-weight: 400;\">Meloxicam interactions<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Taking two or more drugs can sometimes lead to trouble. Meloxicam is no exception. Because of the way it works, meloxicam affects many organs and systems in the body, particularly the blood, stomach, and kidneys. There are, then, a variety of ways that meloxicam can interact with other medications and foods. While not a complete list of interactions, here is how to make sense of some of them:<\/span><\/p>\n<h3 id=\"meloxicam-and-nsaids\"><span style=\"font-weight: 400;\">Meloxicam and NSAIDs<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">As previously stated, meloxicam is an NSAID. When taken with other NSAIDs, including ordinary aspirin or ibuprofen, the risk of side effects increases due to their additive effects. This is because all NSAIDs more or less cause similar side effects, particularly gastrointestinal problems including stomach pain, bleeding, and ulcers. As a general rule, taking two or more NSAIDs should be avoided except under the advice of a doctor. Taking multiple types of NSAIDs will delay it leaving your body and put you at a higher risk of side effects. Acetaminophen, the active ingredient in Tylenol, can acutely be substituted for NSAIDs or used concurrently for treating pain or fever in most cases.<\/span><\/p>\n<h3 id=\"meloxicam-and-bleeding\"><span style=\"font-weight: 400;\">Meloxicam and bleeding<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Meloxicam interferes with the body\u2019s ability to form blood clots. So, when meloxicam is taken with <\/span><span style=\"font-weight: 400;\">blood thinners<\/span><span style=\"font-weight: 400;\"> such as warfarin, there is an increased risk of bleeding episodes, particularly stomach bleeding. This is because NSAIDs also target <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK549795\/\"><span style=\"font-weight: 400;\">COX-1 receptors<\/span><\/a><span style=\"font-weight: 400;\">, which protect the mucus lining of the stomach. Although <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9219316\/#:~:text=The%20MELISSA%20study%2C%20a%20double,an%20improved%20GI%20tolerability%20profile.\"><span style=\"font-weight: 400;\">it targets COX-1 receptors less than other NSAIDs<\/span><\/a><span style=\"font-weight: 400;\">, a physician might avoid or limit prescribing meloxicam with blood thinners. SSRIs (antidepressants), SNRIs (antidepressants), and some anticancer drugs also increase the risk of bleeding and gastrointestinal bleeding when combined with meloxicam.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Some drugs specifically raise the risk of gastrointestinal bleeding, including corticosteroids, some osteoporosis drugs (bisphosphonates), and some anticancer drugs. These, too, need to be used carefully when combined with meloxicam.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">There are several over-the-counter dietary and herbal supplements that also interfere with blood clotting, such as fish oil, garlic, ginkgo, willow bark, krill oil, and saw palmetto. A healthcare professional can provide sound advice about whether to combine these supplements with meloxicam.<\/span><\/p>\n<h3 id=\"meloxicam-and-blood-pressure\"><span style=\"font-weight: 400;\">Meloxicam and blood pressure<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Elevated blood pressure is a common side effect of meloxicam, so taking meloxicam may counteract the effects of medications intended to lower blood pressure. Also, taking meloxicam with <\/span><span style=\"font-weight: 400;\">ACE inhibitors<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">angiotensin II receptor blockers (ARBs)<\/span><span style=\"font-weight: 400;\">, two common types of <\/span><span style=\"font-weight: 400;\">blood pressure medications<\/span><span style=\"font-weight: 400;\">, increases the risk of kidney problems and elevated potassium (hyperkalemia) in seniors or people with existing kidney problems.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Several types of drugs also raise blood pressure. Combining any of them with meloxicam raises the risk of high blood pressure:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Caffeine, alcohol, and nicotine<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Stimulants<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Antidepressants<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Asthma medications<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Decongestants<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Birth control pills<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Migraine medications<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Some immune-suppressing anticancer drugs<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Parkinson\u2019s disease medications<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">These drugs are not necessarily prohibited from taking with meloxicam, but blood pressure should be monitored when taking them together. Some popular herbal remedies and supplements also raise blood pressure, such as ephedra, licorice, and Yohimbe. Again, the risk of high blood pressure increases when these supplements are taken with meloxicam.<\/span><\/p>\n<h3 id=\"meloxicam-and-diuretics\"><span style=\"font-weight: 400;\">Meloxicam and diuretics<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Taking meloxicam with certain types of loop diuretics or thiazide diuretics may lower sodium levels, which can be potentially hazardous, or diminish kidney function. If you\u2019re uncertain what type of diuretic you\u2019re taking, a doctor, pharmacist, or other healthcare provider can help identify it. Therapy will need to be monitored and may need to be modified.<\/span><\/p>\n<h3 id=\"meloxicam-and-the-kidneys\"><span style=\"font-weight: 400;\">Meloxicam and the kidneys<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Meloxicam affects substances that regulate blood flow in the kidneys, changing how well the kidneys eliminate drugs from the body. This can increase the damage to the kidneys caused by other drugs, such as cyclosporine and tacrolimus. Alternatively, meloxicam can decrease the ability of the kidneys to eliminate certain drugs, particularly lithium, a drug used to treat bipolar disorder; methotrexate, a drug used to treat cancer or rheumatism; and pemetrexed, an anticancer drug. This may sound like a good thing, but it actually means that these drugs linger longer in the body at higher concentrations, increasing their toxicity and the likelihood of adverse effects. Again, these drugs may not need to be avoided outright, but their dosing regimens may need to be modified.<\/span><\/p>\n<h2 id=\"how-to-avoid-meloxicam-side-effects\"><span style=\"font-weight: 400;\">How to avoid meloxicam side effects<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Like all medications, meloxicam can have side effects, particularly problems with the stomach and small intestine. A few rules of thumb can help improve the odds:<\/span><\/p>\n<h3 id=\"1-take-meloxicam-as-directed\"><span style=\"font-weight: 400;\">1. Take meloxicam as directed<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Unless instructed to take it only on an as-needed basis, take the daily dose as prescribed. Don\u2019t increase or decrease the dose. Don\u2019t miss a dose and, if you do, don\u2019t take extra medicine to make up for a missed dose.<\/span><\/p>\n<h3 id=\"2-avoid-taking-other-nsaids\"><span style=\"font-weight: 400;\">2. Avoid taking other NSAIDs<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Many OTC pain relievers belong to the same class of drugs as meloxicam, including aspirin. These NSAIDs have many of the same side effects as meloxicam and are eliminated the same way, so it\u2019s a good idea to avoid them while taking meloxicam, unless instructed by your healthcare provider. Sometimes, low-dose aspirin will be prescribed concurrently for cardiovascular purposes.<\/span><\/p>\n<h3 id=\"3-take-meloxicam-with-food\"><span style=\"font-weight: 400;\">3. Take meloxicam with food<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Meloxicam can be taken with or without food. If taking meloxicam produces stomach problems, consider taking meloxicam with food. Meloxicam can also be taken safely with antacids.<\/span><\/p>\n<h3 id=\"4-avoid-taking-meloxicam-long-term\"><span style=\"font-weight: 400;\">4. Avoid taking meloxicam long-term<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">The likelihood of side effects, including serious side effects, increases the longer the medication is taken. To minimize adverse effects, meloxicam is intended to be taken at the lowest possible dose for the shortest duration possible to achieve therapy goals. If a medical condition like rheumatoid <\/span><span style=\"font-weight: 400;\">arthritis<\/span><span style=\"font-weight: 400;\"> requires continual use of pain relievers, a healthcare professional can suggest alternatives to the long-term use of meloxicam.<\/span><\/p>\n<h3 id=\"5-avoid-smoking-and-alcohol\"><span style=\"font-weight: 400;\">5. Avoid smoking and alcohol<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Smoking and drinking alcohol raise the risk of<\/span><a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2016\/020938s024s025,021530s014s015lbl.pdf#page=4\"><span style=\"font-weight: 400;\"> stomach ulcers<\/span><\/a><span style=\"font-weight: 400;\"> in people taking NSAIDs such as meloxicam.\u00a0<\/span><\/p>\n<h3 id=\"6-tell-the-doctor-about-all-medical-conditions\"><span style=\"font-weight: 400;\">6. Tell the doctor about all medical conditions<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">To reduce the risk of side effects, make sure the prescribing doctor is aware of all medical conditions past and present, particularly:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Heart problems including heart disease or heart attack<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">A history of blood clots or stroke<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Ulcers or gastrointestinal bleeding<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fluid retention<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Asthma<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">High cholesterol<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diabetes<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Liver problems<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Kidney problems<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Allergies to NSAIDs<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">The prescribing doctor will also need to know about pregnancy status, breastfeeding, fertility treatments, or any plans on becoming pregnant.<\/span><\/p>\n<h3 id=\"7-tell-the-doctor-about-all-medications-being-taken\"><span style=\"font-weight: 400;\">7. Tell the doctor about all medications being taken<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Many side effects of prescription drugs like meloxicam are simply caused by combining them with the wrong medications. For anyone with a chronic condition like arthritis, it\u2019s helpful to keep a list of all medications used. Prescription drugs, over-the-counter drugs, dietary supplements, and herbal remedies, taken both regularly or rarely should be included. Keep this list on hand so it can be readily shared with a doctor, pharmacist, or other healthcare provider before a prescription is written and filled. Follow their advice if they indicate certain drugs, supplements, or foods should be avoided.<\/span><\/p>\n<h2 id=\"how-to-treat-side-effects-of-meloxicam\"><span style=\"font-weight: 400;\">How to treat side effects of meloxicam<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The response to meloxicam side effects depends on the severity. A healthcare professional will need to be consulted to determine what to do. For mild nausea or stomach upset, taking meloxicam with food or concurrently with an antacid may be enough to mitigate the adverse effect. Bleeding, abdominal pain, chest pain, swelling, or shortness of breath require emergency medical attention. In the setting of a potential drug interaction, meloxicam may need to be reduced or discontinued.<\/span><\/p>\n<h2 id=\"bottom-line-is-meloxicam-safe\"><span style=\"font-weight: 400;\">Bottom line: Is meloxicam safe?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Every drug can be presumed to have both potential benefits and possible risks. Meloxicam is no exception. The drug may provide pain relief and reduction in swelling and inflammation that can be monumental for someone suffering from arthritis. However, the risk of side effects must be respected. Talk to your healthcare provider to determine if the benefits outweigh the risks in your unique situation and whether there are steps you can take to help minimize adverse effects.<\/span><\/p>\n<h2 id=\"expert-takeaway\"><span style=\"font-weight: 400;\">Expert takeaway<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">\u201cMeloxicam is one of the favored prescription NSAIDS, based on convenient once-daily dosing and having less stomach side effects than other class members,\u201d relates Chad Shaffer, MD, member of the  Medical Board. 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<\/g>\n<\/svg>\t\t\t\t\t\t\t\t<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Do you know: What are the main side effects of meloxicam? in 2025 Key takeaways Meloxicam is a nonsteroidal anti-inflammatory drug that is prescribed for arthritis conditions, as an alternative to over-the-counter products like Advil, Aleve, and aspirin. Side effects of meloxicam often involve the gastrointestinal tract, ranging from simple nausea to serious bleeding ulcers; [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-8743","post","type-post","status-publish","format-standard","hentry","category-health-news"],"blocksy_meta":[],"_links":{"self":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts\/8743","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/comments?post=8743"}],"version-history":[{"count":0,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/posts\/8743\/revisions"}],"wp:attachment":[{"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/media?parent=8743"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/categories?post=8743"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/healthmedicinet.com\/review\/wp-json\/wp\/v2\/tags?post=8743"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}