HMN 2026: How Is vaping more harmful than smoking cigarettes? More people incorrectly think so

e-cigarette

A growing number of U.S. adults consider electronic cigarettes (e-cigarettes) more harmful than conventional cigarettes. The findings, by researchers from the UT Southwestern Medical Center and published in Nicotine and Tobacco Research, could have significant implications for public health policymakers, tobacco control strategies, and people who use either of these cigarette types.

“The perception that e-cigarettes are more harmful than cigarettes has been linked to both a decreased willingness to use e-cigarettes for smoking cessation and an increased likelihood of switching from vaping to smoking. Understanding the ramifications of this perception change represents a critical consideration when developing cessation strategies,” said David Gerber, M.D., Professor of Internal Medicine and in the Peter O’Donnell Jr. School of Public Health and Co-Director of the Office of Education and Training in the Harold C. Simmons Comprehensive Cancer Center at UT Southwestern.

Dr. Gerber co-led the study with Cristina Thomas, M.D., Assistant Professor of Dermatology and Internal Medicine, and Alexander Wu, B.S., a medical student at UTSW and the study’s first author.

Cigarette smoking has declined significantly over the past few decades, from a historical peak in 1965 when 43% of U.S. adults reported smoking to about 12% in 2025, according to the Centers for Disease Control and Prevention. However, since e-cigarettes, or “vapes,” were introduced in the U.S. in 2006, their use has steadily grown: Nearly 7% of U.S. adults reported using these devices in 2025.

According to physicians, e-cigarettes are generally thought to be less harmful than conventional cigarettes, which are known to cause cardiovascular disease, pulmonary disease, and several forms of cancer, Dr. Thomas explained. However, a growing awareness of e-cigarettes’ hazards—including exposure to high levels of addictive nicotine and toxic chemicals as well as a propensity to act as a gateway for conventional cigarette smoking—led the Food and Drug Administration to include e-cigarettes in its 2018 anti-smoking campaign aimed at youth called “The Real Cost.” A year later, an outbreak of e-cigarette or vaping product use-associated lung injury (EVALI) occurred, affecting the health of thousands of e-cigarette users.

To learn how these events may have affected public perception of e-cigarettes, Wu and his colleagues analyzed data from the Health Information Nation Trends Survey (HINTS) from 2012 to 2022. This cross-sectional, nationally representative survey sponsored by the National Cancer Institute collects a variety of health data each year.

Using answers from 20,771 survey respondents, the researchers found that the proportion perceiving e-cigarettes as more harmful than conventional cigarettes rose from nearly 3% in 2012 to more than 30% in 2022. Similarly, perceptions of e-cigarettes as less harmful decreased from nearly 51% in 2012 to about 17% in 2022. An analysis of data collected before and after “The Real Cost” campaign and the EVALI outbreak suggests that these events negatively affected public perceptions of e-cigarettes, Wu said.

“Understanding how events like this shape people’s beliefs is key to guiding public health policy and future tobacco control strategies,” Wu said.

Although e-cigarettes are not harmless, Dr. Gerber added, clinicians widely consider them a less harmful alternative to conventional cigarettes. Research has shown that using e-cigarettes to help quit smoking increases the chances of success compared with other nicotine replacements such as patches, lozenges, and gum when combined with behavioral therapy. Negative public perceptions of e-cigarettes might steer people away from using them as a smoking cessation tool or encourage them to choose conventional cigarettes over e-cigarettes, a topic the team plans to explore in future research.

“Our findings show the need to strike a balance in public health messaging that discourages youths from using either product while also ensuring that adults who do smoke have access to accurate information about product risks and cessation options,” Dr. Thomas said.

Publication details

Alexander Wu et al, Association of Vaping-Related Events with Relative Harm Perceptions of E-Cigarettes, Nicotine & Tobacco Research (2026). DOI: 10.1093/ntr/ntag024 academic.oup.com/ntr/advance-a … /ntr/ntag024/8513109

Journal information:
Nicotine and Tobacco Research


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Nicotine & Tobacco Research


Clinical categories

Preventive medicineCommon illnesses & Prevention


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