Piezo 1 Activation Decreases the CDH5-stained Area and Increases Drainage of Lymphatic Vessel Mimetics in Polydimethylsiloxane (PDMS) Chip. (a) Schematic illustration of the 3D lymphatic vessel model used for this study. (b) Fluorescence confocal images of the engineered lymphatic vessels stained for F-actin and CDH5. (c) The relative area of CDH5-stained cellular junctions. (d) Western blot assays verifying the efficient knock-down of Piezo1 in LECs prepared for the drainage measurement. Credit: Nature Neuroscience (2024). DOI: 10.1038/s41593-024-01604-8 A researcher in the Keck School of Medicine of USC’s department of surgery has Read More
