Safety concerns and hidden agenda behind HPV vaccines: another generation of drug-dependent society?
On September 7, 2016, NCI presented a document “Cancer Moonshot’s Blue Ribbon Panel” to National Cancer Advisory Board. It identified 10 priorities for cancer research including HPV vaccination. The document rehashes the same fuzzy approaches that have been used in the last six decades for cancer research and therapy or vaccines with different spins [1].14 The document reminds us of the tactics that were used in 1970s by CDC director for urgently seeking extra fund for swine flu vaccination. Review of an interesting article “The Swine Flu Affair” [11] resembles the scenario that establishment described for targeting young population for HPV or meningitis vaccines and justifying additional funding.
A wide range of vaccine-related health problems including autism (measles vaccines), multiple sclerosis (hepatitis B), menangioencephalitis (Japanese encephalitis), Guillian-Barre syndrome and giant cell arthritis (influenza), encephalomyelitis (semple rabies), neurological problems (e.g., H1N1, swine flu) have been reported in literature. The total number of death and diseases that were caused by polio, swine flu and other specific vaccines, even BCG vaccines are greater than diseases these vaccines were intended to prevent [1, 12–14].15 The rush for HPV vaccination is no exception as described below.
Human papilloma viruses (HPVs) are small heterogeneous family of at least 130 different viruses (HPV types) of double-stranded DNA whose potencies and genomic structures evolve in host and are different from individual to individual, tissue to tissue and time to time. HPVs have been identified in organs/tissues (e.g., skin, larynx, vagina, penis, esophagus, conjunctiva, bronchus, paranasal sinuses, tracheo-bronchial and oral mucosa, anogenital tract, urethra) in diseases such as genital warts, recurrent respiratory papillomatosis, low-grade and high-grade squamous intraepithelial lesions (SILs) and anal, vaginal and cervical cancers [1, 15–17].16
Emphases on production of specific vaccines to inactivate segments of viral structures such as HPVs DNA structures or expression products, while not effective to prevent specific diseases (e.g., cervical cancers), long-term effects of HPV vaccines (Gardasil™, or Cervarix™) could contribute to initiation of health problems during aging, if not sooner. The genomic structures of HPVs in vaccines (e.g., inactivated high potency particles) could disturb host tissues in a variety of mechanisms (e.g., mutations of DNA components or integration into host chromosomes and instability of genomic substructures). Exposure to viral particles and adjuvant (aluminum) in vaccines, along with routine exposures to other immune disruptors are ‘antigen overload’ for immune system that could shift the induction of chronic health problems (e.g., increased asthma, ocular or skin allergies, hot flashes, gastrointestinal conditions or neurological and autoimmune diseases) that are features of aging to younger individuals [1, 18, 19].
Professionals and policy makers in other countries started raising serious questions about the “scientific uncertainties related to the safety of HPV vaccines…Sloppy science, combined with unprofessional and unfair criticism of independent research, such as the one the EMA raised against the diligent Danish researchers, is a serious threat to scientific progress and public health…”.17 Recent clinical data already suggest adverse effects of HPV vaccines, composed of genotype-specific capsid proteins variations (e.g., HPV-16, HPV-6 or HPV-11) or expression of detectable HPVL1 protein and DNA fragments in aluminum-containing adjuvant, of virus-like-particles-VLPs by DNA recombinant methodologies [15, 16].18
We suggested that exposures to specific virus-containing vaccines, by inhibiting/inactivating specific high risks (‘potent’) segments of viral DNA lead to inflammatory conditions that would influence the homeostasis and dynamics (ecosystem) of host microorganisms (e.g., GI track, skin) in young adults. Altering hazard/benefit ratios of microbiota are important contributing factors in ‘antigen overload’ for immunity and cross reactivity of antibodies against antiviral immune complexes and induction of age-like chronic diseases in younger adults. Our observations that newborn guinea pigs born from sensitized parents showed strong allergic reactions upon 1st or 2nd challenge with antigen, suggesting genetic predisposition of fetus [1, 4, 5] are indirectly supported by clinical data [1, 18, 19].
Again, a great deal of investment have been directed to identify details of structures and substructures of microorganisms, carcinogens or expression products and mechanisms of actions of evolving numerous infective agents [e.g., HPV, polio, rous sarcoma, herpes, AIDS, EBOLA, influenza, measles, hepatitis (A, B and C), LPS, meningitis or Zika]. However, what initiates altered tissue response dynamics toward multistep diseases or cancers remains a mystery [1, 11–17].
The hidden short- and long-term agenda behind making HPV or meningitis vaccination as priority projects seem the availability of funds through Obamacare insurance and Moonshot Initiative. There should be no surprise that the cost of individual insurance keeps going up. Sixty-nine cancer centers urged HPV vaccination and thus-far, 80 million doses of HPV vaccines ($200–260/dose) consumed by healthy public [1].19,20
It is painful to project that the sick status of ‘baby boomers’, created half a century ago could be repeated, if not already started, by vaccinating the public with HPV or other vaccines (e.g., meningitis, shingles, flu), whether or not vaccines are contaminated with live viruses. Such fraud approaches could present grave health consequences for future generation (s), if the policy makers, professionals and public do not reflect on the fact that ‘intellectuals’ in health system who were responsible for improving public health are destroying it.