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Hormone Therapy Not Recommended for Prevention of Chronic Conditions in Postmenopausal Women

Medicine, Health Care Hormone Therapy Not Recommended for…

Published: December 12, 2017.
Released by The JAMA Network Journals  

Bottom Line: The U.S. Preventive Services Task Force (USPSTF) recommends against the use of combined estrogen and progestin in postmenopausal women, or estrogen alone in postmenopausal women who have had a hysterectomy, to prevent chronic conditions such as heart disease, dementia and stroke.

Background: The USPSTF routinely makes recommendations about the effectiveness of preventive care services. This latest recommendation statement on the use of hormone therapy in postmenopausal women is an update from 2012. The topic is important to many women because the risk of chronic conditions increase with age; however, whether menopause increases this risk and whether hormone replacement decreases it is uncertain.

How: The USPSTF recommendation statement follows a review of evidence from clinical trials on the benefits and harms of hormone therapy taken orally or applied through the skin.

Related material

The following related elements from The JAMA Network are also available on the For The Media website:

Hormone Therapy for the Primary Prevention of Chronic Conditions in Postmenopausal WomenEvidence Report and Systematic Review for the US Preventive Services Task Force

JAMA Editorial: Menopausal Hormone Therapy for Primary Prevention of Chronic Disease

JAMA Cardiology Editorial: Menopausal Hormone Therapy for the Primary Prevention of Chronic Conditions

JAMA Internal Medicine Editorial: Evidence for Postmenopausal Hormone Therapy to Prevent Chronic Conditions

JAMA Patient Page: Hormone Therapy for Primary Prevention of Chronic Conditions in Postmenopausal Women


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