Retinyl propionate, climbazole improves photodamaged skin

(HealthDay)—Retinyl propionate and climbazole (RPC) is associated with clinical improvement in moderately photodamaged skin for women aged 40 to 70 years, according to a study published online July 22 in the International Journal of Cosmetic Science.

Stacy Hawkins, Ph.D., and colleagues from Unilever Research and Development in Trumbull, Conn., and colleagues recruited 45 healthy Caucasian women, ages 40 to 70 years, with moderately photodamaged skin for a 16-week randomized facial study. Using split-face product application, the authors compared the efficacy of RPC treatment with 0.1 percent retinol, in the same product base formulation, twice daily.

The researchers found that, compared to 0.1 percent retinol treatment, RPC treatment correlated with significant improvement in aging attributes (P

“RPC delivered significant skin antiaging benefits comparable or greater than 0.1 percent retinol, with minimal irritation,” the authors write.

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