Tryptase is involved in the development of early ventilator-induced pulmonary fibrosis in sepsis-induced lung injury

¹ CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain

² Multidisciplinary Organ Dysfunction Evaluation Research Network, Research Unit, Hospital Universitario Dr. Negrin, Barranco de la Ballena, s/n – 4th floor, South wing, Las Palmas de Gran Canaria 35010, Spain

³ Keenan Research Center for Biomedical Science, St. Michael’s Hospital, Toronto, Ontario, Canada

⁴ Department of Anatomy, Pathology Histology, University of La Laguna, Tenerife, Spain

⁵ Department of Clinical Biochemistry, Hospital Universitario NS de Candelaria, Santa Cruz de Tenerife, Spain

⁶ Department of Respiratory Care, Massachusetts General Hospital, Boston, MA, USA

⁷ Department of Anesthesia, Harvard University, Boston, MA, USA

⁸ Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Ontario, Canada