Jan. 10, 2013 ? Stem cells can be grown on biocompatible scaffolds to form formidable tissues such as bone, cartilage, and flesh for correct and metamorphosis of shop-worn or infirm tissue. However, to duty properly, a cells contingency mostly grow in a specific settlement or alignment. An innovative routine for formulating a stretched polymer skeleton that can support formidable hankie architectures is described in an essay in Tissue Engineering, Part C, Methods.
Zu-yong Wang and a group of researchers from National University of Singapore, Nanyang Technological University, KK Women’s and Children’s Hospital, and Duke-NUS Graduate Medical School, in Singapore, grown a reproducible routine that involves stretching a polymer skinny film to furnish scaffolds that can support a expansion of tellurian mesenchymal branch cells. The stretching routine creates orientated 3-dimensional micro-grooves on a aspect of a films, and these formations foster unchanging fixing and elongation of branch cells as they grow and rise into tissues on and around a resorbable scaffold.
The authors benefaction their work in a article, “Biomimetic 3D anisotropic geometries by uniaxial widen of poly(?-caprolactone) films for mesenchymal branch dungeon proliferation, fixing and myogenic differentiation.â€
“The researchers grown a really superb routine to foster dungeon behavior,†says John Jansen, DDS, PhD, Methods Co-Editor-in-Chief and Professor and Chairman, Department of Biomaterials, Radboud University Nijmegen Medical Center, The Netherlands.
Other amicable bookmarking and pity tools:
Story Source:
The above story is reprinted from materials supposing by Mary Ann Liebert, Inc., Publishers, around AlphaGalileo.
Note: Materials might be edited for calm and length. For serve information, greatfully hit a source cited above.
Journal Reference:
- Zu-yong Wang, Erin Yiling Teo, Mark Seow Khoon Chong, Qin-yuan Zhang, Jing Lim, Zhi-yong Zhang, Ming-hui Hong, Eng-san Thian, Jerry Kok Yen Chan, Swee-Hin Teoh. Biomimetic Three-Dimensional Anisotropic Geometries by Uniaxial Stretch of Poly(?-Caprolactone) Films for Mesenchymal Stem Cell Proliferation, Alignment, and Myogenic Differentiation. Tissue Engineering Part C: Methods, 2013; : 130104095453008 DOI: 10.1089/ten.tec.2012.0472
Note: If no author is given, a source is cited instead.
Disclaimer: This essay is not dictated to yield medical advice, diagnosis or treatment. Views voiced here do not indispensably simulate those of ScienceDaily or the staff.
