Adding smartphone-based cognitive-behavior therapy to pharmacotherapy for major depression (FLATT project): study protocol for a randomized controlled trial


1 Department of Clinical Epidemiology, Translational Medical Center, National Center of Neurology and Psychiatry, 4-1-1 Ogawa-Higashi, Kodaira 187-8551, Tokyo, Japan

2 National Center for Cognitive Behavior Therapy and Research, National Center of Neurology and Psychiatry, 4-1-1 Ogawa-Higashi, Kodaira 187-8551, Tokyo, Japan

3 Department of Neuropsychopharmacology, National Institute of Mental Health, National Center of Neurology and Psychiatry, 4-1-1 Ogawa-Higashi, Kodaira 187-8551, Tokyo, Japan

4 Department of Neuropsychiatry, Kochi Medical School, Kochi University, Kohasu, Okoh-cho, Nankokushi 783-8505, Kochi, Japan

5 Department of Psychiatry and Cognitive-Behavioral Medicine, Nagoya City University Graduate School of Medical Sciences, Mizuho-cho, Mizuho-ku, Nagoya 467-8601, Japan

6 Miki Clinic, 1-1-3 Hiranuma, Nishi-ku, Yokohama 220-0023, Japan

7 Department of Neuropsychiatry, Okayama University Hospital, 2-5-1 Shikata-cho Kita-ku, Okayama 700-8558, Japan

8 Department of Field Medicine, Kyoto University Graduate School of Medicine, 46 Shimoadachi-cho, Yoshida Sakyo-ku, Kyoto 606-8501, Japan

9 Departments of Health Promotion and Human Behavior, Kyoto University Graduate School of Medicine/School of Public Health, Yoshida Konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan