Amyloid ? peptide-induced inhibition of endothelial nitric oxide production involves oxidative stress-mediated constitutive eNOS/HSP90 interaction and disruption of agonist-mediated Akt activation


1 Department of Ophthalmology, Georgia Regents University, Health Sciences Campus, 1120 15th St., Augusta 30912, GA, USA

2 Department of Biology, University of Rome ‘Roma Tre’, Via Ostiense, 169, Rome 00154, Italy

3 Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Cusano Milanino 20095, Milan, Italy

4 Department of Kinesiology, College of William and Mary, 200 Stadium Dr., Williamsburg 23186, VA, USA

5 Vascular Biology Center, Georgia Regents University, 1120 15th St., Augusta 30912, GA, USA

6 IRC-FSH, Department of Health Sciences, University of Catanzaro ‘Magna Graecia’, Catanzaro Complesso ‘Ninì Barbieri’, Roccelletta di Borgia 88021, Italy

7 IRCCS San Raffaele Pisana, Via di Val Cannuta, 247, Rome, 00166, Italy