Development of interactive algorithm for clinical management of acute events related to sickle cell disease in emergency department


Sickle cell disease (SCD ORPHA232; OMIM 603903) is a rare hereditary red cell disorder, which global distribution is changed in the last decade due to immigration-fluxes from endemic areas to Western-countries. One of the main clinical manifestations of SCD are the acute painful vaso-occlusive crisis, which cause frequent accesses of SCD patients to the EDs.

This has generated the requirement of feasible tools for emergency givers. In the context of the scientific-Italian-Society for the study of Thalassemias and Hemoglobinopathies (SITE), we developed an algorithm with interactive windows to guide physicians in managing SCD patients in EDs.

Author: Gian Luca ForniGabriele FincoGiovanna GraziadeiManuela BaloccoPaolo RiganoSilverio PerrottaOliviero OlivieriMaria D CappelliniLucia De Franceschi
Credits/Source: Orphanet Journal of Rare Diseases 2014, 9:91

Published on: 2014-06-23

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