Fever in sepsis: is it cool to be hot?


Changes in body temperature are a characteristic feature of sepsis. The study by Kushimoto and colleagues in a recent issue of Critical Care demonstrates that hypothermia is a very important manifestation of infection associated with very high mortality.

Combined with recent data suggesting that febrile patients with infections have the lowest mortality risk, the study raises the question of whether inducing therapeutic hyperthermia might be beneficial in this patient group. Body temperature is easily measured and manipulated in the ICU, and interventional trials defining the most appropriate temperature targets in ICU patients with infections are urgently needed.

One such study is in progress.

Author: Paul J YoungRinaldo Bellomo
Credits/Source: Critical Care 2014, 18:109

Published on: 2014-02-13

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News Provider: EUPB – European Press Bureau

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