How Age-related changes in skin may contribute to melanoma metastases


Age-related Changes in Skin and Melanoma Metastases

As we age, our skin undergoes various changes that can increase the risk of melanoma metastases. Melanoma is a type of skin cancer that can spread to other parts of the body if not detected and treated early.

One of the age-related changes in skin that can contribute to melanoma metastases is the decrease in collagen and elastin production. Collagen and elastin are proteins that help maintain the skin’s structure and elasticity. As we age, the production of these proteins decreases, leading to thinner and more fragile skin that is more susceptible to damage.

Another factor is the accumulation of sun damage over the years. Exposure to UV radiation from the sun can cause DNA damage in skin cells, increasing the risk of developing melanoma. As we age, the cumulative effects of sun exposure can further weaken the skin’s defenses against cancerous growths.

It is important for individuals, especially older adults, to protect their skin from sun exposure by wearing sunscreen, protective clothing, and avoiding prolonged periods in the sun. Regular skin checks and screenings can also help detect any suspicious moles or lesions early on.

By understanding the age-related changes in skin and taking proactive steps to protect against melanoma, individuals can reduce their risk of developing metastatic melanoma and improve their overall skin health.