How Fracture risk is up with prediabetes before menopause transition

Fracture Risk with Prediabetes before Menopause Transition

Fracture Risk with Prediabetes before Menopause Transition

Fracture risk is a significant concern for women, especially during the menopause transition. However, recent studies have shown that prediabetes can further increase the risk of fractures in women before they reach menopause. This article will explore the relationship between prediabetes and fracture risk, providing valuable insights for women in this stage of life.

Understanding Prediabetes

Prediabetes is a condition characterized by higher than normal blood sugar levels, but not high enough to be diagnosed as type 2 diabetes. It is often considered a warning sign that indicates an increased risk of developing diabetes in the future. Prediabetes is commonly associated with insulin resistance, a condition where the body’s cells do not respond effectively to insulin.

Fracture Risk and Prediabetes

Several studies have found a strong association between prediabetes and increased fracture risk in women before they enter menopause. One study published in the Journal of Bone and Mineral Research found that women with prediabetes had a 50% higher risk of fractures compared to women with normal blood sugar levels.

The exact mechanisms behind this increased fracture risk are still being studied. However, it is believed that insulin resistance plays a crucial role. Insulin resistance can lead to decreased bone mineral density and impaired bone quality, making bones more susceptible to fractures.

Prevention and Management

Preventing fractures in women with prediabetes before menopause transition requires a comprehensive approach. Here are some strategies that can help reduce fracture risk:

  • Healthy Lifestyle: Adopting a healthy lifestyle that includes regular exercise, a balanced diet, and weight management can help improve insulin sensitivity and overall bone health.
  • Calcium and Vitamin D: Adequate intake of calcium and vitamin D is essential for maintaining strong bones. Consult with a healthcare professional to determine the appropriate supplementation.
  • Screening and Monitoring: Regular screening for prediabetes and monitoring blood sugar levels can help identify the condition early and take necessary steps to manage it effectively.
  • Medical Intervention: In some cases, medication may be prescribed to manage prediabetes and reduce fracture risk. Consult with a healthcare professional for personalized advice.


Women with prediabetes before menopause transition face an increased risk of fractures. Understanding this association and taking proactive measures to manage prediabetes can help reduce fracture risk and promote overall bone health. By adopting a healthy lifestyle, ensuring adequate calcium and vitamin D intake, and seeking appropriate medical guidance, women can mitigate the impact of prediabetes on their bone health during this critical stage of life.