Late-life basin compared with prevalent amiable cognitive impairment, increasing risk of dementia


Dec. 31, 2012 ? Depression in a organisation of Medicare recipients ages 65 years and comparison appears to be compared with prevalent amiable cognitive spoil and an increasing risk of dementia, according to a news published Online First by Archives of Neurology, a JAMA Network publication.

Depressive symptoms start in 3 percent to 63 percent of patients with amiable cognitive spoil (MCI) and some studies have shown an increasing insanity risk in people with a story of depression. The mechanisms behind a organisation between basin and cognitive decrease have not been done transparent and opposite mechanisms have been proposed, according to a investigate background.

Edo Richard, M.D., Ph.D., of a University of Amsterdam, a Netherlands, and colleagues evaluated a organisation of late-life basin with MCI and insanity in a organisation of 2,160 community-dwelling Medicare recipients.

“We found that basin was compared to a aloft risk of prevalent MCI and dementia, occurrence dementia, and course from prevalent MCI to dementia, though not to occurrence MCI,” a authors note.

Baseline basin was compared with prevalent MCI (odds ratio [OR], 1.4) and insanity (OR, 2.2), while baseline basin was compared with an increasing risk of occurrence insanity (hazard ratio [HR], 1.7) though not with occurrence MCI (HR, 0.9). Patients with MCI and coexistent basin during baseline also had a aloft risk of course to insanity (HR, 2.0), generally vascular insanity (HR, 4.3), though not Alzheimer illness (HR, 1.9), according to a investigate results.

“Our anticipating that basin was compared cranky sectionally with both MCI and insanity and longitudinally usually with insanity suggests that basin develops with a transition from normal discernment to dementia,” a authors conclude.

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The above story is reprinted from materials supposing by JAMA and Archives Journals.

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Journal Reference:

  1. Richard E, Reitz C, Honig LH, et al. Late-Life Depression, Mild Cognitive Impairment, and Dementia. Archives of Neurology, 2012; DOI: 10.1001/jamaneurol.2013.603

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