Lung ultrasound in quantifying lung water in septic shock patients


Fourteen patients (67%) were male, the median age was 62 years (IQR 55 to 68) and
eight (38%) patients had cardiac comorbidities. In median, SAPS 3 was 64 (IQR 60 to
74), ICU length of stay was 3 days (IQR 2 to 8) and seven patients (33%) died within
30 days of ICU admission. All patients were mechanically ventilated and treated according
to guidelines 3]. The median number of B-lines was 15 (IQR 10 to 30) and the median (IQR) NT-proBNP,
EVLWI and oxygenation index (OI) were 7,800 ng/l (3,690 to 15,050), 11 ml/kg (IQR
8 to 18) and 9.2 (5.7 to 15.7), respectively. None of the characteristics differed
significantly between survivors and nonsurvivors. The number of B-lines correlated
to EVLWI (? = 0.45, P = 0.04; r2 = 0.20, P = 0.04), but not to NT-proBNP (? = -0.42, P = 0.06), OI (? = 0.25, P = 0.31) or ICU length of stay (? = 0.14, P = 0.57). On Bland-Altman analysis, mean differences and 95% limits of agreements between
B-lines and EVLWI was 4.9 (-14.5 to 24.5), and 5.9 (-3.5 to 15.3) when assessing observer
agreement. The ICC between methods was 0.52 (95% CI = -0.17 to 0.81) and 0.90 (95%
CI = 0.73 to 0.92) between observers.