Optimal debulking surgery is postulated to be useful in survival of ovarian cancer patients. Some studies highlighted the possible role of bowel surgery in this topic.
We wanted to evaluate the role of bowel involvement in patients with advanced epithelial ovarian cancer who underwent optimal cytoreduction.
Methods:
Between 1997 and 2004, 301 patients with advanced epithelial cancer underwent surgery at Department of Gynecological Oncology of Centro di Riferimento Oncologico (CRO) National Cancer Institute Aviano (PN) Italy. All underwent maximal surgical effort , including bowel and upper abdominal procedure, in order to achieve optimal debulking (R
PFS and OS were compared with residual disease, grading and surgical procedures.
Results:
Optimal cytoreduction was achieved in 244 patients (81.0%); R0 in 209 women (69.4.%) and R
Pelvic peritonectomy and upper abdomen procedures were carried out in 202 (67.1%) and 82 (27.2%) patients respectively. Among the 284 patients available for follow-up, PFS and OS were significantly better in patients with R
Among the 229 patients with optimal debulking (R
In the 199 patients with R0, PFS and OS were significantly better (p
Conclusions:
Optimal cytoreduction (R
Bowel involvement in G3 patients, carries instead the same risk of recurrence for PFS.
Author: Giorgio GiordaAngiolo GadducciEmilio LuciaRoberto SorioValentina E BounousFrancesco SopracordevoleAndrea TinelliGustavo BaldassarreElio Campagnutta
Credits/Source: Journal of Ovarian Research 2014, 7:72
Published on: 2014-07-09
Tweet
News Provider: 7thSpace Interactive / EUPB Press Office
Social Bookmarking
RETWEET This! | Digg this! | Post to del.icio.us | Post to Furl | Add to Netscape | Add to Yahoo! | Rojo
There are no comments available. Be the first to write a comment.