1 Department of Critical Care Medicine, University of Pittsburgh School of Medicine, 3600 Forbes Avenue, Iroquois Building Suite 400A, Pittsburgh 15213, PA, USA
2 Department of Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
3 Department of Pulmonary and Critical Care Medicine, Lahey Hospital and Medical Center, Burlington, MA, USA
4 University of Pittsburgh Clinical and Translational Science Institute (CTSI), Pittsburgh, PA, USA