3D genome features point to possible therapeutic target for aggressive and deadly pediatric brain tumors

Credit: Cell (2024). DOI: 10.1016/j.cell.2024.06.023 Posterior fossa group A (PFA) ependymoma are rare, treatment-resistant pediatric tumors of the central nervous system that originate in the brain and spinal cord. They have the highest recurrence rate and poorest prognosis of all childhood cancers due to the lack of effective treatment. Hope is on the horizon now that an international research team led by scientists at Baylor College of Medicine in Texas, U.S., and the Research Institute of the McGill University Health Center (RI-MUHC) in Montreal, Canada, have identified unique 3-dimensional features Read More

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