A new target for treatment of one type of macular degeneration

Tert and Terc specific antisense oligonucleotides (ASOs) suppress CNV growth. A) Schematic representation of the ASO treatment in laser-induced CNV mouse model. B) Representative confocal images of FITC- isolectin B4 stained RPE/choroid/scleral flatmount showing CNV lesion C) Quantification of CNV volume. Credit: Biochimica et Biophysica Acta (BBA)—Molecular Basis of Disease (2024). DOI: 10.1016/j.bbadis.2024.167156 A new study in mice hints at the promise of an eventual alternative treatment option for the “wet” version of age-related macular degeneration (AMD). Researchers determined in mice that an enzyme related to cell growth and division Read More

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