New work presented at the 2024 congress of EULAR—The European Alliance of Associations for Rheumatology—assesses the power of multi-modal analysis of synovial tissue inflammation in treatment-naïve patients with rheumatoid arthritis (RA). The hope is to identify predictive biomarkers for treatment response. The synovial tissue inflammation seen in RA shows a high degree of heterogeneity—which may be a factor in people’s variable response to treatments. We also know that distinct synovial tissue macrophage subsets regulate inflammation and remission in rheumatoid arthritis. The potential of high-throughput analyses has been shown, and these Read More