Pain-sensing neurons are stained green and red to show activity under a microscope. Credit: Tao Deng/NCATS Stem Cell Translation Laboratory/NIH Researchers have just taken the most fine-grained look to date at inflammatory pain: increased sensitivity to pain that follows an immune response to a wound, infection, sunburn, arthritis, or other trigger. In mouse and computer model experiments, the team identified thousands of molecular interactions—most not previously known—between pain-initiating neurons, or nociceptors, and different types of immune cells. These interactions could help explain why pain hypersensitivity sometimes occurs during inflammation—and could Read More