New tuberculosis vaccine candidate shows promise with post-translational modifications

Whole blood derived from six adult donors who were inoculated with BCG in their childhood was cultured with MDP1 alone, MDP1 in combination with G9.1, or in combination with the negative form of G9.1(Neg G9.1). The combination of mMDP1+G9.1 induced the highest amount of IFN-gamma. Credit: Niigata University Tuberculosis is still one of the deadliest infectious diseases, causing over one million deaths each year worldwide. Additionally, about one-fourth of the world’s population carries Mycobacterium tuberculosis without showing any symptoms, and most of these carriers do not develop the disease. The Read More

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