Graphical abstract. Credit: The American Journal of Human Genetics (2024). DOI: 10.1016/j.ajhg.2024.04.017 Each cell contains a set of instructions in its DNA that determines which genes are expressed and which are silenced. The correct programming of these so-called epigenetic programs, including DNA methylation, is essential for fertilization and development. A team of researchers from the University of Münster have for the first time identified the DNA methylation program behind sperm production (spermatogenesis) in the human. They found that during spermatogenesis the entire genome is reprogrammed. Moreover, when they analyzed cells Read More
