Aortic Pressure Gradients and B-mode speckle tracking on transgenic mice. Credit: Nature Cardiovascular Research (2024). DOI: 10.1038/s44161-024-00502-3 Cardiovascular disease often culminates in heart failure, a hallmark of which is fibrosis, a form of tissue scarring. Cardiac fibrosis initially repairs damaged heart tissue, but it can quickly become excessive and pathological. Identifying the mechanisms behind fibrosis is a focal point in cardiovascular research, and now scientists at the Lewis Katz School of Medicine at Temple University have discovered a critical genetic mechanism driving the process—and they have identified a novel target Read More