Team finds exportin 1 governs immunosuppressive functions of myeloid-derived suppressor cells in tumors

Credit: Cellular & Molecular Immunology (2024). DOI: 10.1038/s41423-024-01187-1 A team of Roswell Park Comprehensive Cancer Center experts led by Hemn Mohammadpour, DVM, Ph.D., has conducted research that offers new insights into tumor biology and may lay the groundwork for more effective cancer immunotherapy. Their preclinical findings were published June 20 in the journal Cellular & Molecular Immunology. “We discovered that a protein highly expressed by tumor cells and targeted in treatments for cancers like multiple myeloma is also highly expressed by myeloid-derived suppressor cells,” notes Saeed Daneshmandi, Ph.D., study first Read More

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