Why overweight body hampers its immune response to SARS-CoV-2

Recent studies have indicated that individuals who are overweight or obese may have a compromised immune response to the SARS-CoV-2 virus, which causes COVID-19. This research highlights the importance of maintaining a healthy weight to protect against severe illness and complications from the virus.

According to a study published in the journal The Lancet Diabetes & Endocrinology, individuals who are overweight or obese are more likely to experience a weakened immune response when infected with SARS-CoV-2. The study found that excess body weight can impair the body’s ability to fight off the virus, leading to a higher risk of severe illness and hospitalization.

One of the reasons behind this impaired immune response is the chronic low-grade inflammation that often accompanies obesity. Excess fat tissue releases pro-inflammatory molecules, which can disrupt the normal functioning of the immune system. This can result in a reduced ability to mount an effective immune response against viral infections like SARS-CoV-2.

Furthermore, obesity is associated with various underlying health conditions such as diabetes, cardiovascular disease, and respiratory issues, which can further weaken the immune system. These comorbidities increase the risk of severe COVID-19 symptoms and complications.

It is important to note that the impact of excess weight on immune response is not limited to COVID-19. Previous research has shown that obesity can also impair the body’s ability to fight off other respiratory infections, such as influenza.

Given these findings, it is crucial for individuals who are overweight or obese to take steps towards achieving a healthy weight. This includes adopting a balanced diet, engaging in regular physical activity, and seeking support from healthcare professionals or weight management programs.

Additionally, public health initiatives should focus on promoting healthy lifestyles and weight management to reduce the burden of COVID-19 and other infectious diseases. This can include providing access to nutritious food, promoting physical activity, and raising awareness about the risks associated with excess weight.

In conclusion, research has shown that being overweight or obese can hamper the body’s immune response to SARS-CoV-2. Maintaining a healthy weight is crucial for protecting against severe illness and complications from COVID-19. By addressing the underlying factors contributing to excess weight, individuals can improve their immune function and overall health.