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Katherine Scangos, M.D. (left), oversees transcranial magnetic stimulation. Credit: TMS and Neuromodulation Program/UC San Francisco Some 30 to 40% of patients do not respond to medications for depression and obsessive-compulsive disorder (OCD), but half of them could be helped by a noninvasive in-office procedure. To mark National Mental Health Awareness Month in May, we talk Read More
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Time series plot of leptospirosis across flood phases in the study area. a Alappuzha in 2018. b Pathanamthitta in 2018. c Alappuzha in 2019. d Pathanamthitta in 2019. Credit: International Journal of Health Geographics (2024). DOI: 10.1186/s12942-024-00372-9 A recent study, published by researchers at the Faculty of ITC in the International Journal of Health Geographics, Read More
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Loneliness is not a disease. And yet it is a significant health problem. Depression, heart disease or dementia—people who are permanently lonely have a higher risk of becoming ill. The team led by Dr. Jana Lieberz from the University Hospital Bonn (UKB), who also conducts research at the University of Bonn, and Prof. Dr. Dirk Read More
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Oxidative stress is known to exacerbate fibrosis and autoimmunity. In a new study, researchers from Japan have investigated the effects of a dietary antioxidant supplement—Twendee X—on oxidative stress and fibrosis in a mouse model of SSc, an intractable autoimmune disease. Given its effectiveness in other oxidative stress-related diseases including dementia, Twendee X holds the promise Read More
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Credit: Brunel University The idea that autistic people lack empathy is simply short-sighted and non-autistic people may find it just as hard to put themselves in someone else’s shoes, a study suggests. A paper in the journal Autism flips the script on the often-said stereotype that autistic people have difficulty imagining how others feel. Participants Read More
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A Cleveland Clinic-led team of scientists and physicians have discovered that the immune checkpoint protein VISTA can directly turn off tumor-fighting T-cells during immunotherapy and resist treatment. The study, published in Science Immunology, explains that VISTA can bind to a protein called LRIG1 in T cells, which was previously only thought to promote bone and Read More
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Roughly one in five cancer patients benefit from immunotherapy—a treatment that harnesses the immune system to fight cancer. Such an approach to beating cancer has seen significant success in lung cancer and melanoma, among others. Optimistic about its potential, researchers are exploring strategies to improve immunotherapy for cancers that don’t respond well to the treatment, Read More
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A single-photon emission computerized tomography (SPECT) scan uses a radioactive substance (Techne gas) and a special camera to create lung images. CT-derived functional imaging is a novel image processing method without the need for inhalation of special gas or injection of contrast. This image shows close similarities between areas of lung function obtained on same Read More
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Figure portrays the mean values of all Environmental Burden indicators by race/ethnicity. Credit: Journal of Alzheimer’s Disease Reports (2024). DOI: 10.3233/ADR-240020 A study by Duke and Columbia Universities finds older, non-white adults are more likely to live in areas with higher air pollution and near toxic disposal sites, among or environmental injustices, potentially underlying their Read More
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Levels of air pollution and road traffic noise levels of nurses from the Danish Nurse Cohort at the cohort baseline aggregated at the municipality level. Credit: Alzheimer’s & Dementia (2024). DOI: 10.1002/alz.13814 Results from a new study suggest that long-term exposure to air pollution leads to increased risk in dementia in Denmark. “We also find Read More
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A researcher holds a flask containing human cerebral organoids similar to those used in the CWD study. Credit: NIAID A new study of prion diseases, using a human cerebral organoid model, suggests there is a substantial species barrier preventing transmission of chronic wasting disease (CWD) from cervids—deer, elk and moose—to people. The findings, from National Read More
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Credit: Wellness Gallery Catalyst Foundation from Pexels Aerobic training is known to regulate blood pressure more effectively when practiced in the evening than in the morning. Researchers who conducted a study of elderly patients at the University of São Paulo’s School of Physical Education and Sports (EEFE-USP) in Brazil concluded that evening exercise is better Read More
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Two different KDs induce cellular senescence. Credit: Science Advances (2024). DOI: 10.1126/sciadv.ado1463 A strict “keto-friendly” diet popular for weight loss and diabetes, depending on both the diet and individual, might not be all that friendly. A new study led by researchers at The University of Texas Health Science Center at San Antonio (UT Health San Read More
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A US teenager died of cardiac arrest after taking part in a social media challenge daring people to eat a single extremely hot tortilla chip, an autopsy revealed Thursday. Harris Wolobah, a 14-year-old from Massachusetts, died in September after taking part in the so-called “One Chip Challenge”—which involved a single chip produced by Paqui, dusted Read More
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The American Gastroenterological Association’s (AGA) new evidence-based Clinical Practice Guideline on Endoscopic Eradication Therapy of Barrett’s Esophagus and Related Neoplasia, published today in Gastroenterology, establishes updated guidance for Barrett’s esophagus patients. A precursor to esophageal cancer, Barrett’s esophagus is a condition in which the cells in the esophagus have been replaced with non-cancerous abnormal cells. Read More
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Subjective disgust experience is associated with and predicted by distributed brain regions. a, Thresholded VIDS. b, Thresholded transformed VIDS ‘activation pattern’. c, The conjunction between VIDS and transformed ‘activation pattern’. Images thresholded at q?
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Stroke is the leading cause of disability worldwide and the second leading cause of death, but the right early intervention can prevent severe consequences. A new study led by investigators from Brigham and Women’s Hospital and collaborators describes how the team developed a new test by combining blood-based biomarkers with a clinical score to identify Read More
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For patients with binge eating disorder (BED), a web-based cognitive behavioral self-help intervention leads to significant reductions in binge eating episodes and improvements in mental health outcomes, according to a study published online May 16 in JAMA Network Open. Luise Pruessner, from Heidelberg University in Germany, and colleagues examined the effectiveness of a web-based cognitive Read More
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Sleepaway camp can be a lot of fun for kids, but only if they’re ready for the experience. And that’s the tough part—figuring out as a parent when a child is ready to stay away from home, and what they’ll need while they’re at camp, said Dr. Laurel Williams, a professor of psychiatry and behavioral Read More
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The U.S. Food and Drug Administration on Thursday approved a new drug to treat patients with an advanced form of deadly lung cancer. Importantly, tarlatamab (Imdelltra) is only for patients who have exhausted all other options to treat extensive-stage small cell lung cancer. “The FDA’s approval of Imdelltra marks a pivotal moment for patients battling Read More
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It’s a right of passage into Mike Locksley’s Maryland football program to participate in the ‘3 H’s’ meeting. Newcomers stand before teammates, coaches and staff to share about their hero, a highlight of their life and a hardship. It’s one of a few crucial Terps mental health touchpoints. Head coach always goes first. By Locksley Read More
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Credit: Cell Reports Methods (2024). DOI: 10.1016/j.crmeth.2024.100777 A team of medical researchers at the National Children’s Medical Center, Children’s Hospital, Fudan University, in China, has developed a technique to freeze and thaw brain tissue without causing damage. In their study, published in the journal Cell Reports Methods, the group tested bathing brain organoid tissue in Read More
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A schematic overview of the study and a graphic explanation of the static and dynamic r factor scores. Mental well-being is measured with 45 items on six clinical domains, that is, anxiety, depression, PTSD, impulsivity, sleep and alcohol and nicotine use. Credit: Nature Mental Health (2024). DOI: 10.1038/s44220-024-00242-0 Following traumatic experiences, many individuals demonstrate remarkable Read More
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Metformin 500mg tablets. Credit: public domain People who use metformin are less likely to develop a myeloproliferative neoplasm (MPN) over time, indicating that the treatment may help prevent the development of certain types of cancers, according to a study published in Blood Advances. Metformin is a therapy used to treat high blood sugar in people Read More
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A petri dish holding microporous scaffold implants. Credit: Michele Santillan A new microporous scaffold functions as a minimally-invasive surveillance method to identify rejection prior to graft injury in a mouse model, according to a study published in Science Advances. These sensors are a first step towards developing a tool which could provide physicians with vital Read More
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Graphical abstract. Journal of Clinical Investigation (2024) https://doi.org/10.1172/JCI173789 A study from the laboratory of Shi-Yuan Cheng, Ph.D., professor in the Ken and Ruth Davee Department of Neurology’s Division of Neuro-oncology, has identified novel mechanisms underlying RNA splicing events within glioma tumor cells, mechanisms which may serve as novel therapeutic targets, according to findings published in Read More
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A significant link between the use of electronic cigarettes and earlier age of asthma onset in U.S. adults was reported by UTHealth Houston researchers May 17, 2024 in JAMA Network Open. Led by first author Adriana Pérez, Ph.D., MS, professor of biostatistics and data science at UTHealth Houston School of Public Health, the research found Read More
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Rutgers researchers, aided by international collaborators, have tracked the devastation war has made on Ukraine’s hospital system. Hundreds of hospitals in Ukraine have been forced to close or operate at a reduced capacity since Russia’s invasion of the Eastern European country in February 2022. Damage, destruction and supply shortages caused by the war have impaired Read More
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An HIV vaccine candidate developed at the Duke Human Vaccine Institute triggered low levels of an elusive type of broadly neutralizing HIV antibodies among a small group of people enrolled in a 2019 clinical trial. The finding, reported May 17 in the journal Cell, not only provides proof that a vaccine can elicit these antibodies Read More
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Men are at greater risk than women of the major health effects of diabetes (types 1 and 2), proposes a long term study published online in the Journal of Epidemiology & Community Health. Rates of cardiovascular disease, leg, foot, and kidney complications, and the sight-threatening eye disease diabetic retinopathy are all higher in men, regardless Read More
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