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The latest findings from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021, published in The Lancet, provide new insights into health challenges and the risk factors that are driving them. An increase in people experiencing risk factors associated with metabolism, such as high systolic blood pressure (SBP), high fasting plasma glucose Read More
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The latest findings from the Global Burden of Disease Study (GBD) 2021, published in The Lancet, forecast that global life expectancy will increase by 4.9 years in males and 4.2 years in females between 2022 and 2050. Increases are expected to be largest in countries where life expectancy is lower, contributing to a convergence of Read More
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The implementation of primary health care (PHC) over the last two decades has prevented more than 300,000 child deaths in four Latin American countries, and could prevent more than 140,000 by 2030 in a scenario of economic crisis. This is the main conclusion of a study coordinated by the Barcelona Institute for Global Health (ISGlobal) Read More
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The more time spent on social media, the greater the likelihood that children and young people will both smoke and/or vape, suggests research published online in the respiratory journal Thorax. Clocking up a weekday tally of seven or more hours was associated with a more than a doubling in risk among 10 to 25-year-olds, the Read More
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A multipronged primary care quality improvement initiative increases early human papillomavirus (HPV) vaccine initiation across racial/ethnic, sociodemographic, insurance, and geographic groups, according to a study presented at the annual meeting of the Pediatric Academic Societies, held from May 2 to 6 in Toronto. Caitlin Miller, from Nemours Children’s Health in Delaware Valley, Delaware, and colleagues Read More
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A new study suggests that the tobacco company Philip Morris International (PMI), is successfully increasing public trust in industry-funded science by portraying itself as a generous supporter of scientific research while simultaneously concealing its involvement through third parties. The paper, published in Frontiers in Communication, was co-authored by researchers in the Tobacco Control Research Group Read More
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University of Florida researchers have developed a system designed to identify patients at high risk of discontinuing buprenorphine treatment for opioid use disorder. An FDA-approved prescription drug, buprenorphine is one of three commercially available treatments for opioid use disorder proven to be effective in treating both pain and addiction. In a study published in the Read More
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Benjamin Toll, Ph.D., Lisa Fucito, Ph.D., and colleagues developed a clinical trial for e-cigarette cessation that was meant to mimic real-world conditions. Credit: Medical University of South Carolina The first U.S. trial of varenicline for e-cigarette cessation shows promising results and warrants larger-scale trials, the researchers say. Researchers from Yale Cancer Center and MUSC Hollings Read More
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An electron transmission micrograph from the study shows the problematic peptide 33-mer DGP with spiky structures that can open the intestinal barrier. Credit: Bielefeld University Today is International Celiac Day. Celiac disease is a chronic autoimmune condition that occurs in around 1% of the world’s population. It is triggered by the consumption of gluten proteins Read More
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Amyloid ? accelerates age-related proteome-wide protein insolubility. Credit: GeroScience (2024). DOI: 10.1007/s11357-024-01169-1 It has long been known that a hallmark of Alzheimer’s disease, and most other neurodegenerative diseases, is the clumping together of insoluble protein aggregates in the brain. During normal disease-free aging, there is also an accumulation of insoluble proteins. To date, approaches to Read More
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Micrograph showing a lymph node invaded by ductal breast carcinoma, with extension of the tumor beyond the lymph node. Credit: Nephron/Wikipedia Assisted reproductive techniques (ART) in young women with high-risk genes who have survived breast cancer do not increase the risk of cancer recurrence or adversely affect the resulting pregnancies and babies, show results from Read More
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Credit: Clinical Gastroenterology and Hepatology (2024). DOI: 10.1016/j.cgh.2024.04.003 The rate of colorectal cancer screenings more than doubled when patients were given a choice between which type of screening they wanted—a take-home kit or colonoscopy—compared to those who were only offered the colonoscopy, according to new research led by the Perelman School of Medicine at the Read More
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Leanne Redman, Ph.D., director of the Reproductive Endocrinology and Women’s Health Laboratory at Pennington Biomedical. Credit: Pennington Biomedical Research Center For many generations, society has embraced the idea that pregnant women are “eating for two.” That adage is frequently invoked as mothers-to-be are encouraged to abandon diets and overindulge in every food craving in the Read More
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AVA and AVB have distinct membrane potential ranges and dynamics. Credit: Science Advances (2024). DOI: 10.1126/sciadv.adk0002 Researchers at Sinai Health and the University of Toronto have uncovered a mechanism in the nervous system of the tiny roundworm C. elegans that could have significant implications for treating human diseases and advancing robotics. The study, led by Read More
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In a new study, researchers looked at whether lonely people are more prone to problems such as depression and psychosis. Based on medication use, the correlation is clear. “We have found a correlation between loneliness and several mental health problems,” says Associate Professor Rubén Rodríguez-Cano at NTNU’s Department of Psychology. “The risk of a lonely Read More
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An Expert Insight, published in the journal Transplantation, highlights health equity, disparity and inequality in organ transplantation along the continuum of care and across organ types. The authors provide a guide to transplant centers for the use of disparity-sensitive measures to monitor and address health disparities in transplantation and to redress long-standing inequities and inequalities Read More
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Many people are concerned about residues of chemicals, contaminants or microplastics in their food. However, it is less well known that many foods also contain toxins of completely natural origin. These are often chemical compounds that plants use to ward off predators such as insects or microorganisms. These substances are found in beans and potatoes, Read More
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Cell-based therapies can potentially restore normal immune function and treat organ failure in sepsis. Medical researchers have embarked on clinical trials and pre-clinical studies to investigate the efficacy and safety of such therapies, signaling a promising new avenue in sepsis treatment. Credit: Professor Xiangming Fang of Zhejiang University, China Imagine the human body mounting an Read More
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Radar chart evaluation of each app’s objective quality domain according to the user version of the Mobile Application Rating Scale (uMARS), with results divided by country. Credit: Journal of Medical Internet Research (2024). DOI: 10.2196/51628 The Journal of Medical Internet Research has published the results from the first phase of the validation study on the Read More
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Researchers from Japan successfully applied polarization-sensitive optical coherence tomography (PS-OCT) to assess various properties of the collagen fibers that make up the sclera, the outer white of the eye. PS-OCT could determine the direction of these fibers at different layers of the sclera, enabling researchers to compare these features between eyes with different ocular pathologies. Read More
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No pharmacological medication currently available can cure or slow down Parkinson’s disease. However, based on an extensive literature review recently published in the journal Journal of Neurology, Neurosurgery & Psychiatry, researchers from Aarhus University conclude that physical exercise should be a significant factor in the treatment of Parkinson’s patients. “Based on current evidence, we propose Read More
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Number of men with a screen-positive PSA test result and with a prostate cancer diagnosis according to the baseline PSA value. For men with baseline PSA
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US President Joe Biden’s administration formally proposed on Thursday reclassifying marijuana as a less dangerous drug, a historic shift that would bring federal policy more in line with public opinion. “No one should be in jail merely for using or possessing marijuana. Period,” Biden said in a video statement. “Far too many lives have been Read More
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For decades, researchers have assumed that people overestimate the risk of dramatic causes of death, such as road traffic accidents. The reason given for this was that such deaths are the subject of far greater media attention than more significant but less spectacular mortality risks. However, a study at the Technical University of Munich (TUM) Read More
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Representative case of the independent internal patient cohort shows a 54-year-old male patient who suffered from an IDH-mutated oligodendroglioma WHO grade 2 that was correctly classified by all algorithms. Credit: Cancers (2024). DOI: 10.3390/cancers16061102 Machine learning (ML) methods can quickly and accurately diagnose mutations in gliomas—primary brain tumors. This is shown by a recent study Read More
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SRP-001’s absent hepatotoxicity is due to lack of NAPQI formation and maintenance of hepatic tight junction integrity. Credit: Scientific Reports (2024). DOI: 10.1038/s41598-024-61791-z A recent publication in Scientific Reports unveils a promising non-opioid pain treatment developed by a team led by Dr. Hernan Bazan, the John Ochsner Endowed Professor of Cardiovascular Innovation at Ochsner Health. Read More
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Research led by the University of Southampton shows particular regions of England have suffered over a decade of increasing mental health inequalities, but finds the picture varies greatly across different parts of the country. The study, in collaboration with the University of Liverpool, examines the relationship between socioeconomic conditions within local areas and the mental Read More
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Wholegrain products and legumes. Credit: Nicole Nerger In Europe, 1.55 million people die every year due to a poor diet. This is the conclusion of a recent study by Friedrich Schiller University Jena, the Institute for Sustainable Agriculture and Food Economics (INL) and the nutriCARD Competence Cluster. The researchers analyzed the importance of nutrition for Read More
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The coverage of variants yielded by testing technologies is indicated. Structural variants may entail duplications, deletions, and unbalanced insertions, while positional changes may involve balanced translocations, insertions, or inversions. Credit: Science China Press Congenital heart disease (CHD) includes a variety of structural malformations affecting the heart and blood vessels. With growing understanding of the molecular Read More
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Proportion of REGARDS study participants developing aTRH by number of adverse social determinants of health, overall. Credit: Journal of the American Heart Association (2024). DOI: 10.1161/JAHA.123.031695 People were more likely to develop a type of treatment-resistant hypertension when they experienced adverse effects of economic and social conditions that influence individual and group differences in health Read More
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