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Dr. Collin Costello checks for skin cancer. Credit: Mayo Clinic Skin cancer is the most common cancer in the U.S. Each year, more than 6 million adults are treated for skin cancer, according to the Centers for Disease Control and Prevention. Dr. Collin Costello, a Mayo Clinic dermatologist, says anyone can get skin cancer, but Read More
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MauiWES testing and survey event in February 2024. Credit: University of Hawaii at Manoa Nearly half of the Maui residents affected by the fires experienced a decline in health compared to a year ago, and they continue to face difficulties accessing medical care and medications. These are just two of the findings from the most Read More
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The COVID-19 pandemic was challenging for many adolescents, disrupting their schooling and social/emotional development. Drawing on national data, a large study finds that how adolescents’ brains were wired before the pandemic predicted their stress, negative emotions, and overall mental health during its height— making them more vulnerable or more resilient. The findings, reported in the Read More
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Distribution of legal experts’ answers. Credit: European Journal of Neurology (2024). DOI: 10.1111/ene.16334 Dementia often leads to the appointment of a legal guardian for the individual affected, as their legal capacity diminishes as the disease progresses. Cognitive symptoms of dementia include, e.g., memory impairment and language deficits, while neuropsychiatric symptoms include, e.g., impulsivity and sensitivity Read More
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SHOX2 ccfDNAm and its association with survival in melanoma patients treated with palliative immunotherapy. Credit: Clinical Chemistry (2024). DOI: 10.1093/clinchem/hvad230 If melanoma spreads, there are various therapies that can be used. However, there is still insufficient research into who responds to which therapy and whether resistance may develop over time. In a new study, Dr. Read More
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In an important step toward more effective gene therapies for brain diseases, researchers from the Broad Institute of MIT and Harvard have engineered a gene-delivery vehicle that uses a human protein to efficiently cross the blood-brain barrier and deliver a disease-relevant gene to the brain in mice expressing the human protein. Because the vehicle binds Read More
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Organoid of a patient with colon cancer, treated (right) and not treated with the chemotherapy etoposide. The treatment causes DNA damage and a reduction in protein synthesis. This triggers a stress signal that causes the cells to die. Orange: marker for DNA damage. Green: marker for protein synthesis. Credit: Netherlands Cancer Institute Chemotherapy kills cancer Read More
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Acute stress decreased the third party’s willingness to punish the violator and the severity of the punishment, and increased their willingness to help the victim. Created with Adobe Illustrator. Credit: Huagen Wang (CC-BY 4.0, creativecommons.org/licenses/by/4.0/) Being stressed while witnessing injustice may push your brain towards altruism, according to a study published on May 14 in Read More
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Allostatic load quantification in the ABCD Study. a, Bifactor configuration of AL. Values represent loadings to each factor shown on the arrows pointing to individual measures. Measures of the model fit (CFI, RMSEA and SRMR) are provided on the bottom left. b, Correlation heatmap of the individual variables, age and AL score (Pearson correlation test Read More
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An Australian-first study by the Registry of Senior Australians (ROSA) investigating the use of blood sugar-lowering medications among residents with diabetes in aged care homes nationwide, has revealed the rising use of insulin and ongoing high use of another antidiabetic drug, sulfonylureas, both associated with a heightened risk of hypoglycemia. Also known as low blood Read More
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Credit: King-Wai Yau Laboratory In what they believe is a solution to a 30-year biological mystery, neuroscientists at Johns Hopkins Medicine say they have used genetically engineered mice to address how one mutation in the gene for the light-sensing protein rhodopsin results in congenital stationary night blindness. The condition, present from birth, causes poor vision Read More
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Meta Getman and her husband had spent more than three years struggling with infertility—including four rounds of intrauterine insemination (IUI), three rounds of in vitro fertilization (IVF) and a six-month pause to weigh next steps—before eventually opting to conceive through IVF using donor eggs. Their twin daughters are now 7 years old, and their family Read More
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Unintentional drowning rates were higher in 2020, 2021, and 2022 than in 2019 and are highest among children aged 1 to 4 years, according to research published in Morbidity and Mortality Weekly Report. Tessa Clemens, Ph.D., from the CDC in Atlanta, and colleagues compared unintentional drowning death rates in 2019 to those in 2020, 2021, Read More
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by Noam N. Levey, KFF Health News Heather Crivilare was a month from her due date when she was rushed to an operating room for an emergency cesarean section. The first-time mother, a high school teacher in rural Illinois, had developed high blood pressure, a sometimes life-threatening condition in pregnancy that prompted doctors to hospitalize Read More
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Both acute hepatitis C (AHC) and hepatitis C virus (HCV)-related cirrhosis incidence were up substantially globally from 1990 to 2019 in reproductive-aged women, according to a study published online April 19 in the Journal of Global Health. Yanzheng Zou, from the School of Public Health at Nanjing Medical University in China, and colleagues used data Read More
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The U.S. Food and Drug Administration has approved a kit that will allow women to collect their own vaginal sample for HPV screening, a move that could increase early detection in those at risk for cervical cancer. Women will be able to swab themselves in privacy at a doctor’s office, clinic or pharmacy, and the Read More
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Treatment-induced WM neuroplasticity changes. Connectometry results displaying the significant segments of the tracts with longitudinal QA increases significantly associated with singing group versus control group between T1 and T2 (?T2–T1; left) and longitudinal QA change correlation with improved naming (right). Credit: eneuro (2024). DOI: 10.1523/ENEURO.0408-23.2024 Cerebrovascular accidents, or strokes, are the most common cause of Read More
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Intravascular imaging using neuro optical coherence tomography (nOCT). The nOCT probe is compatible with standard neurovascular microcatheters, integrating with the procedural workflow used in clinical routine. nOCT captures high-resolution three-dimensional optical data sets providing volumetric microscopy of tortuous cerebral arteries, surrounding structures, and therapeutic devices. Credit: Science Translational Medicine (2024). DOI: 10.1126/scitranslmed.adl4497 A large international Read More
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Credit: Cell (2024). DOI: 10.1016/j.cell.2024.04.015 By examining the immune modulations of tumors during the day, scientists from the University of Geneva and the LMU Munich are demonstrating their impact on the diagnosis and management of patients. The currently most promising anti-tumor treatments are immunotherapies, which aim to boost the action of the patients’ immune system Read More
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Patients with very advanced solid tumors saw no significant improvement in overall survival after receiving systemic therapy, according to a study published in JAMA Oncology by researchers at The University of Texas MD Anderson Cancer Center and Yale Cancer Center. The findings provide further evidence to help oncologists counsel patients that additional cancer-directed therapy is Read More
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Volunteers rode exercise bikes as part of the the trial. Credit: University of Aberdeen An active lifestyle can change how the body burns saturated and unsaturated fat according to new research from the University of Aberdeen. In the study, published in Nature Communications, researchers investigated how different types of fat are used by the body, Read More
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Shared fingerprints of anti-PF4 antibodies in VITT and VITT-like disorders after adenovirus infection. Credit: New England Journal of Medicine (2024). DOI: 10.1056/NEJMc2402592 New research led by Flinders University and international experts is expanding understanding of vaccine-induced immune thrombocytopenia and thrombosis (known as VITT). At the height of the COVID-19 pandemic in 2021, VITT emerged as Read More
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A microscopy image shows an enhanced natural killer T cell (blue) attacking a human multiple myeloma cell (magenta). Credit: Lili Yang lab/UCLA Immunotherapies have revolutionized cancer treatment by harnessing the body’s own immune system to attack cancer cells and halt tumor growth. However, these therapies often need to be tailored to each individual patient, slowing Read More
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In a study published in Nature, Christoffer Clemmensen and colleagues demonstrate a new use of the weight loss hormone GLP-1. GLP-1 can be used as a “Trojan Horse” to smuggle a specific molecule into the brain of mice, where it successfully affects the plasticity of the brain and results in weight loss. “I consider the Read More
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PD-1 is required for neonatal heart regeneration. Credit: Nature Cardiovascular Research (2024). DOI: 10.1038/s44161-024-00447-7 When the heart is injured, as in a myocardial infarction, the damaged heart muscle cannot regenerate—instead, scar tissue forms. Cardiomyocytes, the heart muscle cells that generate contractile force, are lost for good. Yet, in mouse models, the hearts of newborns regenerate Read More
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Credit: PLOS ONE (2024). DOI: 10.1371/journal.pone.0300274 A combined team of psychologists from the University of Milano-Bicocca and the Scientific Institute, IRCCS E. Medea, Child Psychopathology Unit, both in Italy, has discovered what might be a marker for autism that could diagnose a child as young as 6 months. In their study, published in PLOS ONE, Read More
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Early identification of stroke type could be key to harnessing the benefits of very early in-ambulance blood pressure lowering treatment in patients with suspected acute stroke, according to new research. The findings were presented at the 10th European Stroke Organization Conference in Basel, Switzerland and simultaneously published in the New England Journal of Medicine. Professor Read More
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Two major supermarket chains, Aldi and Hy-Vee, are recalling brands of cream cheese because of a potential risk for salmonella. No actual illnesses linked to the products have yet been reported, but Hy-Vee said it’s announcing the recall of Hy-Vee Cream Cheese Spread “out of an abundance of caution due to the potential for contamination Read More
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Computer brain simulation. Credit: Brain Simulation Section, BIH, Charité – Universitätsmedizin Berlin For the first time, researchers led by Professor Dr. Petra Ritter’s team have succeeded in explaining the propagation of traveling waves of activity in the human brain using a computer simulation. Previous studies indicate that these waves are important for various cognitive functions Read More
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Infographic: “Alzheimer’s Disease Without Symptoms. How is That Possible?” Credit: Netherlands Institute for Neuroscience Everyone experiences aging in their own way, and factors such as genetics, lifestyle and environment play a role in this process. Some individuals reach the age of 90 or even 100 in good health, without medications or brain disease. But how Read More
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