Spontaneous vasomotion detection. Credit: eLife (2024). DOI: 10.7554/eLife.93721.3 Compared with computers, the brain can perform computations with a very low net energy supply. Yet our understanding surrounding how the biological brain manages energy is still incomplete. What is known, however, is that the dilation and constriction cycles of blood vessels, or vasomotion, spontaneously occur in […]
Climbing stairs is associated with a longer life, according to research presented at ESC Preventive Cardiology 2024, a scientific congress of the European Society of Cardiology (ESC). “If you have the choice of taking the stairs or the lift, go for the stairs as it will help your heart,” said study author Dr. Sophie Paddock […]
“Childhood” and “dementia” are two words we wish we didn’t have to use together. But sadly, around 1,400 Australian children and young people live with currently untreatable childhood dementia. Broadly speaking, childhood dementia is caused by any one of more than 100 rare genetic disorders. Although the causes differ from dementia acquired later in life, […]
Three years after the federal government launched the Canada-wide early learning and child-care plan (CWELCC), our study conducted through the Atkinson Center for Society and Child Development at the University of Toronto finds mixed results in terms of the plan’s ambitions to improve families’ access to affordable child care. Across the country care is less […]
Almost a quarter of US children with symptoms of a brain injury or concussion are not checked for the condition, with younger children particularly likely to be overlooked, a new national study finds. The research, which is published in the journal Brain Injury, also shows that children with symptoms or a diagnosis of a brain […]
A study in more than 3,000 US counties, with 315 million residents, has suggested that air pollution is linked with stress and depression, putting under-65-year-olds at increased risk of dying from cardiovascular disease. The research is presented today at ESC Preventive Cardiology 2024. “Our study indicates that the air we breathe affects our mental well-being, […]
Researchers have developed tiny, flexible devices that can wrap around individual nerve fibers without damaging them. The researchers, from the University of Cambridge, combined flexible electronics and soft robotics techniques to develop the devices, which could be used for the diagnosis and treatment of a range of disorders, including epilepsy and chronic pain, or the […]
A new study by researchers at Brigham and Women’s Hospital suggests a common brain network exists between heart rate deceleration and depression. By evaluating data from 14 people with no depression symptoms, the team found that stimulating some parts of the brain linked to depression with transcranial magnetic stimulation (TMS) also affected heart rate, suggesting […]
In the United States this year alone, there will be an anticipated 2,001,140 new cancer cases—leading to an estimated 611,720 related deaths. That’s 5,480 new cases and 1,680 deaths every day. And, according to a recent CNN report, cancer cases among younger people are rising sharply. The American Cancer Society-reported cancer risks rise greatly with […]
Credit: Nataliya Vaitkevich from Pexels Millions of people around the world live with diabetes mellitus. Many of them have medication and specific dietary management approaches to help them maintain stable blood sugar levels. However, recent innovations, such as inhaled insulin, the hormone made by the pancreas, which controls blood sugar, have sparked hope for more […]
Categorical operationalizations of dose–response relationships between PA and diseases of interest as estimates of relative risk for each 1 mMET-hour/week category of PA derived from ‘drpa’ R package. Credit: Environment International (2024). DOI: 10.1016/j.envint.2024.108667 Physical activity in natural environments prevent almost 13,000 cases of non-communicable diseases a year in England and save treatment costs of […]
A research team from the School of Nursing, LKS Faculty of Medicine of the University of Hong Kong (HKUMed), found positive effects of tai chi and aerobic exercise on sleep quality, psychological well-being, physical function, and circadian rhythm in patients with advanced lung cancer. The study, conducted over a four-year period, discovered additional advantages in […]
Graphical abstract. Credit: Cell Metabolism (2024). DOI: 10.1016/j.cmet.2024.01.015 Aging, a phenomenon that affects every individual, is a natural part of the human condition but one that often induces anxiety. These feelings are paired with health conditions and illnesses that accompany the aging process, all of which decrease lifespan, the amount of healthy and active years, […]
There is increasing evidence that implicit bias—non-conscious attitudes toward specific groups—is a source of racial inequities in certain aspects of health care, and lawmakers are taking note. Since the tragic murder of George Floyd in May 2020, wherein a Black man was killed by police, several U.S. federal and state legislators have introduced proposals declaring […]
Vaping is now more common than cigarette smoking among young people, according to a new report coordinated by the University of Glasgow and commissioned by the World Health Organization. This echoes research that has found the popularity of vaping among young people in the UK has surged in recent years. The number of children experimenting […]
Patricia Creque describes herself as “one of those people who has music in my head and am always ready to dance.” Peripheral artery disease (PAD), however, had made it difficult for her to dance—or even walk. “For years I had such issues with my legs,” said Creque, 69, of Wyomissing. “I had no idea what […]
School lunches will soon contain less added sugars and salt under new nutrition standards announced by the U.S. Department of Agriculture on Wednesday. “We all share the goal of helping children reach their full potential,” Agriculture Secretary Tom Vilsack said in a news release announcing the changes. “Like teachers, classrooms, books and computers, nutritious school […]
Credit: Scientific Reports (2024). DOI:10.1038/s41598-024-52588-1 University of Waterloo researchers have invented a digital medical imaging system that significantly improves the cancer detection process to deliver immediate results and enable swift, effective treatment for all types of cancer. The Photon Absorption Remote Sensing (PARS) system, an innovative, built-from-scratch technology, is faster than traditional cancer-detection methods and […]
A screenshot of the infant gut model. From top to bottom: bacteria, milk sugar, lactic acid, and acetic acid. Nutrients like milk sugar enter from the left and flow to the right. Meanwhile, bacteria convert them into substances like lactic acid. These substances also flow to the right and can be further converted by other […]
Men are still often afforded a great deal of power and privilege in society due to their gender, however, they also experience disproportionate rates of negative psychosocial outcomes. Men, for instance, have higher mortality rates, lower life expectancy, and are more likely to die by suicide. Yet, despite those challenges, men are less likely than […]
Credit: Journal of the American College of Cardiology (2024). DOI: 10.1016/j.jacc.2024.02.009 A multicenter study led by Vanderbilt University Medical Center (VUMC) and Lipscomb University College of Pharmacy in Nashville has identified a potential new treatment for acute heart failure, a leading cause of hospitalization and death. The drug, dapagliflozin, was initially approved for the treatment […]
Correlation between body mass index (BMI) and very low frequency (VLF) amplitude of fluctuation (AFVLF) in brain regions. Left: Statistical map of the voxelwise correlation between AFVLF with BMI. AFVLF was positively associated with BMI in brain regions indicated on the red-yellow color scale. Right: Correlation plot illustrating the relationship between mean AFVLF averaged across […]
The widespread use of alcohol and e-cigarettes among adolescents is “alarming”, according to a report released on Thursday by the World Health Organization’s (WHO) European branch, which recommended measures to limit access. Based on survey data from 280,000 young people aged 11, 13 and 15 in Europe, Central Asia and Canada, the WHO said it […]
For the past year, police Detective Tim Lillard has spent most of his waking hours unofficially investigating his wife’s death. The question has never been exactly how Ann Picha-Lillard died on Nov. 19, 2022: She succumbed to respiratory failure after an infection put too much strain on her weakened lungs. She was 65. For Tim […]
Frailty is a well-established predictor of complications and death after surgery. However, patients over 65 who undergo a high-risk operation in the emergency room are at significantly increased risk of postoperative complications and death in comparison to the same patients who are assessed solely on their level of frailty, according to a study published in […]
The mitochondria in the liver change their shape as soon as food is perceived. The image shows an electron micrograph of the mitochondria in liver cells. Credit: S. Henscke/Max Planck Institute for Metabolism Research What happens in the body when we are hungry and see and smell food? A team of researchers at the Max […]
It’s an idea as old as modern medicine and as new as the latest medical research. No matter how you look at health equity, the conversation involves contradictions. But at its core are fundamental questions about illness and health, say experts who have watched the conversation move from the fringes of scholarly debate to the […]
Baseline (6 p.m.) related changes in cognitive performance, speed in processing time and metabolic parameters after oral administration of creatine versus placebo when pooled at 3 points (0 p.m., 2 a.m., 4 a.m.). Creatine administration led to significant improvements in word memory task (WMT), speed in processing time in WMT, language, logic, and numeric tasks, […]
Consumers need clearer information about the nutritional content and processing of meat and dairy alternatives when they are buying food, according to a new study. Overall, the research from the London School of Hygiene & Tropical Medicine (LSHTM) found that plant-based alternatives are more environmentally friendly than animal-based products, and can be healthier. Their findings, […]
Researchers at the Francis Crick Institute, the National Cancer Institute (NCI) of the U.S. National Institutes of Health (NIH) and Aalborg University in Denmark, have found that vitamin D encourages the growth of a type of gut bacteria in mice which improves immunity to cancer. Reported in Science, the researchers found that mice given a […]
Diagnosing rare Mendelian disorders is a labor-intensive task, even for experienced geneticists. Investigators at Baylor College of Medicine are trying to make the process more efficient using artificial intelligence. The team developed a machine learning system called AI-MARRVEL (AIM) to help prioritize potentially causative variants for Mendelian disorders. The study is published in NEJM AI. […]
An international group of noise experts from the Copenhagen Cancer Institute (Denmark), the Swiss Tropical and Public Health Institute (Swiss TPH), the Perelman School of Medicine at the University of Philadelphia (U.S.) and the Department of Cardiology at the Mainz University Medical Center have analyzed recent epidemiological data and found strong evidence that transportation noise […]
Substance use during pregnancy and postpartum may impact areas of the brain associated with what psychologists and neuroscientists call “affective empathy,” or the emotional response experienced as a result of others’ emotions, a new study suggests. Researchers exposed both mothers who used substances during the perinatal period [start of pregnancy until one year after birth], […]
Investigators in the Smidt Heart Institute at Cedars-Sinai and colleagues report that women with type 2 diabetes diagnosed with hypertension before age 50 may benefit from intensive blood pressure treatment. The findings, published in Diabetes Care, show the risk of developing cardiovascular disease is reduced in women with type 2 diabetes diagnosed with hypertension in […]
Young-onset breast cancer (YOBC) with germline BRCA pathogenic variants (PVs) is associated with an increased risk for all-cause mortality if diagnosed within 10 years after childbirth, according to a study published online April 19 in JAMA Network Open. Zhenzhen Zhang, Ph.D., M.P.H., from the Oregon Health & Science University in Portland, and colleagues examined whether […]
Rotator cuff anatomy. The bursa is a thin, fluid-filled sac originally thought to protect tendons in the rotator cuff by providing a cushion between the tendons and adjacent bones. While repairing injuries to the rotator cuff tendons, surgeons often remove the bursa because they suspect it is a source of shoulder inflammation and pain. Credit: Stavros […]
Graphical abstract. Credit: Journal of Medicinal Chemistry (2024). DOI: 10.1021/acs.jmedchem.3c02451 Research appearing in the Journal of Medicinal Chemistry shows for the first time SARS-CoV-2, the virus responsible for COVID-19, can be inhibited from replicating in living cell cultures using a compound that targets “Mac-1,” a protein key to defending SARS-CoV-2 against the human immune response. […]
At the height of the pandemic, timely access to COVID-19 testing was crucial for curbing the spread of the disease and informing treatment decisions. Studies have unveiled racial and ethnic disparities in COVID-19 infection rates, clinical outcomes, and access to treatment and testing. However, until now, there has been a gap in research specifically examining […]
U.S. recalls of foods for salmonella, foreign objects or undeclared allergens are rampant nowadays and the highest they’ve been since 2020, a watchdog group warns. “Everyone needs to do better: food producers, regulators and lawmakers,” said Teresa Murray, consumer watchdog at U.S. Public Interest Research Group (PIRG). “We shouldn’t have to worry that everything from […]
As many patients already know, urinary tract infections (UTIs) can recur despite the use of antibiotics. So, it’s welcome news that the U.S. Food and Drug Administration on Wednesday approved Pivya (pivmecillinam) to fight bacterial UTIs. “UTIs are a very common condition impacting women and one of the most frequent reasons for antibiotic use,” Dr. […]
Ways in which artificial intelligence is being developed to manage and treat erectile dysfunction. AI, artificial intelligence; ED, erectile dysfunction. Credit: Sanchez, D., Slovacek, H. and Wang, R. In a review published in the journal of UroPrecision, researchers from the University of Texas McGovern Medical School reveal how artificial intelligence (AI) is setting a new […]
Human activities have transformed and degraded Earth’s natural systems. But it’s not just the planet that endures the harms of things like pollution and climate change. Changes like rising ocean temperatures and CO2 levels have cascading effects that threaten the future of humans. In this Q&A, adapted from the April 22 episode of Public Health […]
A quality improvement (QI) initiative to standardize care for babies in the NICU following surgery at the University of Rochester Medical Center (URMC) correlated with fewer unplanned intubations and improved mortality rates. The study, “Reducing Unplanned Intubations in the Neonatal Intensive Care Unit After Children’s Surgery: A Quality Improvement Project,” streamlined care following surgery in […]
Tumor-resident microbiota ETBF together with NOD1 expression predict a poor response to chemotherapy in breast cancer. Credit: Wei Ma, Lu Zhang, Weilong Chen, Zhaoxia Chang, Juchuanli Tu, Yuanyuan Qin, Yuwen Yao, Mengxue Dong, Jiajun Ding, Siqin Li, Fengkai Li, Qiaodan Deng, Yifei Yang, Tingting Feng, Fanrong Zhang, Xiying Shao, Xueyan He, Lixing Zhang, Guohong Hu, […]
Many researchers and clinicians advise the parents of a deaf child waiting for a cochlear implant to avoid sign language and focus exclusively on spoken language. This is due to the widespread belief that exposing a deaf child to sign language actually interferes with the learning of spoken language after the implant has restored hearing. […]
DNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIH A new paper by Dana-Farber Cancer Institute scientists lays the foundation for targeted therapies to inhibit the activation of nuclear factor kappa B (NF-?B), a transcription factor that plays a role in various autoimmune and inflammatory diseases and cancers. The […]
Cancer Survivors Reporting Loneliness Experience Higher Mortality Risk, New Study Shows. Credit: American Cancer Society A new study led by researchers at the American Cancer Society (ACS) showed people surviving cancer who reported feeling more lonely experienced a higher mortality risk compared to survivors reporting low or no loneliness. Researchers observed the highest mortality risk […]
Child maltreatment is a serious public health issue in the United States, particularly affecting young children who are most vulnerable due to their dependence on caregivers. Infants under two years old account for over one-quarter, or 28.1%, of all maltreatment cases in the U.S., and infants under one year of age experience the highest rate […]
Antibiotic treatment of adults hospitalized with moderate COVID-19 is associated with clinical deterioration, despite the drugs being given to over 40% of patients, according to new research being presented at this year’s ESCMID Global Congress (formerly ECCMID) in Barcelona, Spain (27-30 April) The findings underscore the need to discourage indiscriminate prescribing and improve antibiotic stewardship […]
In global crises like the COVID-19 pandemic, it is vital that scientists step forward to engage with the public and help deliver medical and scientific advice in a friendly, digestible and open format. While the traditional way for scientists to do this is by responding to media requests, alternatives, including collaborating with illustrators and local […]
During epidemics of Ebola, COVID-19, Zika and other public health emergencies, effective communication of public health messages is crucial to control the spread of disease, maintain public trust, and encourage compliance with health measures. In a new evidence review to be given at this year’s ESCMID Global Congress (formerly ECCMID) in Barcelona, Spain (27-30 April), […]
Despite progress in combating antimicrobial resistance (AMR) in the U.S. since its peak during the COVID-19 pandemic, hospital-acquired AMR infections remain well above pre-pandemic levels, according to a major new study examining AMR before, during, and after the COVID-19 pandemic in 120 US hospitals. The study was led by Dr. Christina Yek from the US […]
Living at higher altitudes in India is linked to an increased risk of stunted growth, with children living in homes 2,000 meters or more above sea level 40% more at risk than those living 1,000 meters below, finds research published in BMJ Nutrition Prevention & Health. Children living in rural areas seem to be the […]
Both social isolation, defined as the objective state of having few connections with others, and loneliness, which is a subjective negative feeling of being alone, adversely impact the body and mind. In contrast, some individuals can be socially isolated and yet lead healthy lives without experiencing loneliness. However, comprehensive research on the mechanisms through which […]
In Humphreys County, Mississippi—about 70 miles north of the state capital, in the heart of the fertile Delta region—a third of the residents live in poverty. In Belzoni, the county seat, there are just a handful of health care clinics. The town’s only major hospital closed more than a decade ago, around the same time […]
Today’s NHS faces severe time constraints, with the risk of short consultations and concerns about the risk of misdiagnosis or delayed care. These challenges are compounded by limited resources and overstretched staff that results in protracted patient wait times and generic treatment strategies. Staff can operate with a surface level view of patient data, relying […]
Credit: Christina Morillo from Pexels Better heart health may mean middle-aged Black women are less likely to show cognitive decline than those with poor heart health, a study has found. Researchers said the study highlights the importance of heart health in protecting the brain. “Better cardiovascular health in women in their 40s is important to […]
Chemical targeting of the bromodomains of EP300/CBP causes reduced cell growth in medulloblastoma cells, compared with HAT domain targeting. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-47102-0 Medulloblastoma (the most common malignant childhood brain tumor) is separated into four molecular groups, with Group 3 bearing the worst prognosis. By studying EP300 and CBP, critical proteins in Group […]
Caregiving travel—such as taking a child to school or a parent to the doctor—can be associated with stress and decreased happiness among women but not men, according to a University of Michigan study. The imbalance, the researchers say, is a reflection of how society—and transportation services and infrastructure—has historically valued travel for jobs more than […]
Middle Eastern and Arab American populations may have higher rates of Alzheimer’s disease and related cognitive impairments, but researchers don’t exactly know because these populations aren’t identifiable in national datasets. That’s because historically, Middle Eastern and Arab American populations haven’t been included as a distinct ethnic group in the U.S. Census, making it difficult to […]
A new tool to identify infants most at risk for severe respiratory syncytial virus (RSV) illness could aid pediatricians in prioritizing children under age 1 to receive a preventive medication before RSV season (October-April), according to Vanderbilt University Medical Center (VUMC) research published in Open Forum Infectious Diseases and to be presented at the American […]
Three more African countries have joined a rollout of malaria vaccines targeting millions of children in a continent that accounts for 95 percent of malaria deaths, the UN said Thursday. Africa accounts for approximately 94 percent of global malaria cases, according to the World Health Organization. Most of the deaths are of children. Benin, Liberia […]
DPABINet, a sophisticated enhancement of the DPABI software suite, streamlines the intricate analysis of brain networks through fMRI data, providing researchers of all expertise levels with user-friendly access to insights into the brain’s complex network architecture. Credit: Science China Press DPABINet, developed by Dr. Chao-Gan Yan’s team at the Institute of Psychology, Chinese Academy of […]
A new study published in the journal Animal-Human Interactions reveals that emotional turmoil experienced by dog owners after their pet has been stolen is like that of losing a loved one such as a caregiver losing their child. The findings empirically support the notions that the “owner” or guardian roles and relationships equate to familial […]
In a paper published in Science Bulletin, a Chinese team of scientists presented a global study of over 10,000 microbiome samples from pregnant women and mapped links between maternal microbiomes and pregnancy disorders. It found distinct microbial patterns in gut, vaginal and oral microbiomes associated with healthy pregnancy versus complications like gestational diabetes and preterm […]
The study showed that the bivalent vaccine was better at neutralizing more recent viral variants, such as omicron and its subvariants. Credit: Fábio Rodrigues-Pozzebom/Agência Brasil A major bivalent COVID-19 vaccine induces production of neutralizing antibodies against the coronavirus that circulated at the start of the pandemic as well as subvariants of omicron, albeit less abundantly, […]
France’s health agency said it ordered Perrier to destroy two million bottles of its sparkling water suspected of ‘faecal’ contamination. Perrier destroyed two million bottles of its famous sparkling water suspected of being contaminated with “fecal” bacteria under government orders, the public health agency said Thursday. The announcement of the destruction was the latest blow […]
Chlamydia trachomatis inclusion bodies (brown) in a McCoy cell culture. Credit: public domain Chlamydia and gonorrhea are the two most common sexually transmitted infections (STIs) in the United States, impacting 2.4 million in 2021, and the number is rising. A recent study of individuals ages 15 to 60 measuring and comparing treatment rates for these […]
New research points to an economic factor that might be overlooked when considering why drug-related deaths among Black Americans increased significantly after 2010 in U.S. regions reporting heightened fentanyl activity: job losses that followed the Great Recession. Researchers analyzed data on employment, demographics, drug seizures and causes of death for over 200 counties in the […]
“Sentinel macrophages” at the gateway of the liver phagocytose the gut-derived pathogens and produce the anti-inflammatory proteins, thereby suppressing surrounding inflammatory responses. Credit: Yu Miyamoto Osaka University researchers have discovered liver resident macrophages’ pivotal role in defending against gut bacteria and related substances entering via the portal vein, particularly under compromised intestinal barrier conditions. Identified […]
In the era after the introduction of publicly funded in vitro fertilization (IVF) mandating elective single embryo transfer, the multifetal pregnancy rate decreased significantly for IVF, but the contribution of ovulation induction and intrauterine insemination (OI/IUI) to multifetal pregnancy still needs attention, according to a new study from ICES and Queen’s University. Twins, triplets, and […]
Compared to heterosexual women, bisexual women died 37% sooner and lesbian women 20% sooner, according to results from one of the largest studies to examine sexual orientation-related inequities in mortality and the first to differentiate between lesbians and bisexual women. The findings are published April 25 in JAMA. Decades of research have documented that sexual […]
Mouse hippocampus with rat cells (red) and nuclei of both mouse and rat cells (blue). Credit: M. Khadeesh Imtiaz, Columbia University Irving Medical Center If mice ever wonder what it’s like to experience the world as a rat, some are now able to live that dream, at least when it comes to the sense of […]
Warning letters from Medicare can safely cut prescribing of a powerful but risky antipsychotic, according to a new study at Columbia University Mailman School of Public Health. Researchers used Medicare data to study the effects of the letters on hundreds of thousands of older adults with dementia. They found a significant and lasting reduction in […]
Credit: Kyoto University A research team led by Professor Haruhisa Inoue (Department of Cell Growth and Differentiation) derived iPS cells (iPSC) from ?-synucleinopathy patients with early-onset familial Parkinson’s disease (PD) carrying the ?-synuclein (SNCA) A53T mutation and differentiated them into cerebral cortical neurons in an attempt to decipher the underlying molecular mechanisms involved in neurodegeneration […]
(from left) Prof. Niels Lemmermann; Prof. Natalio Garbi, Dr. Maria Belen Rodrigo and Prof. Christian Kurts. Credit: University Hospital Bonn / Alessandro Winkler Chemokines are signaling proteins that orchestrate the interaction of immune cells against pathogens and tumors. To understand this complex network, various techniques have been developed to identify chemokine-producing cells. However, it has […]
Garrett Clark estimates he has spent about six years in the Sanpete County Jail, a plain concrete building perched on a dusty hill just outside this small, rural town where he grew up. He blames his addiction. He started using in middle school, and by the time he was an adult he was addicted to […]
Tobacco smoking is negatively associated with resolution of psoriasis symptoms, according to a study published in the April issue of Tobacco Induced Diseases. Yan Qiang, from the School of Medicine at Tongji University in Shanghai, and colleagues explored the influence of smoking on treatment efficacy in patients with psoriasis. The analysis included 560 patients with […]
Credit: Maurício Mascaro from Pexels Myopia, or the need for corrected vision to focus or see objects at a distance, has become a lot more common in recent decades. Some even consider myopia, also known as nearsightedness, an epidemic. Optometry researchers estimate that about half of the global population will need corrective lenses to offset […]
“Tennis is a relationship,” says Tashi Duncan (Zendaya) in director Luca Guadagnino’s new film Challengers. However, this relationship is not simply between the game and the player. Rather the heart of tennis, and perhaps of all competition, is a three-way relationship between two contestants and a third person. Their presence, and observation, is what gives […]
Trends in total deaths and the proportion of home deaths in Japan from 2015 to 2021. Credit: JMA Journal (2024). DOI: 10.31662/jmaj.2023-0165 A new study has revealed the increased home death ratio in Japan during the coronavirus disease 2019 (COVID-19) pandemic. High population density, large numbers of patients infected with COVID-19, and areas with numerous […]
The antibiotic vancomycin, recommended as first-line treatment for infection caused by the deadly superbug C. difficile (C. diff), may not be living up to its promise, according to new research from the University of Houston College of Pharmacy. C. diff infection is the leading cause of death due to gastroenteritis in the U.S. It causes […]
A cancer drug was found to be ineffective in preventing recurrence of kidney cancer in patients who recently underwent tumor removal surgery, according to a clinical trial published in the Journal of Clinical Oncology. More than 80,000 new cases of kidney cancer are diagnosed each year, according to the American Cancer Society, and roughly 14,000 […]
Most ex-cons are unlikely to receive substance use treatment following their release from prison, even though odds are high they are struggling with addiction, a new study finds. National estimates suggest as many as 85% of inmates leave prison with some form of substance abuse problem, researchers said. But only 17% of ex-cons on Medicaid […]
Until three years ago nobody had developed a vaccine against any parasitic disease. Now there are two against malaria: the RTS,S and the R21 vaccines. Adrian Hill, director of the Jenner Institute at the University of Oxford and chief investigator for the R21 vaccine, tells Nadine Dreyer why he thinks this is a great era […]
For patients with relapsed or refractory CD7-positive leukemia or lymphoma, sequential CD7 chimeric antigen receptor (CAR) T-cell therapy followed by haploidentical hematopoietic stem-cell transplantation (HSCT) is safe and effective, with remission seen for most patients, according to a study published in the New England Journal of Medicine. Yongxian Hu, M.D., Ph.D., from the Zhejiang University […]
This image shows the effect of protein-like polymers (red) in the brain cells of a mouse model. The nanoscale polymers are designed to alter the interaction between two proteins to combat oxidative stress in the cells. Credit: Johnson Lab/UW–Madison A newly developed nanomaterial that mimics the behavior of proteins could be an effective tool for […]
TRMT10C protein and mRNA levels are increased in AD cell and animal models and cortex samples of AD patients. Credit: Molecular Psychiatry (2024). DOI: 10.1038/s41380-024-02421-y A team of researchers at Johannes Gutenberg University Mainz (JGU) has identified a mechanism that causes mitochondrial dysfunction in Alzheimer’s patients resulting in a reduction of the supply of energy […]
The risk for postoperative respiratory complications is similar among patients undergoing emergency surgery regardless of preoperative glucagon-like peptide 1 receptor agonist (GLP-1 RA) use, according to a research letter published online April 22 in the Journal of the American Medical Association. Anjali A. Dixit, M.D., M.P.H., from Stanford University in California, and colleagues used a […]
Genome-wide CRISPR dropout screen identifies PRMT5 as an essential gene for survival of ER?+?/RB1-deficient breast cancer cells. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-46495-2 Shutting down a gene called PRMT5 stopped metastatic estrogen receptor-positive (ER+) breast cancer cells from growing after they acquired resistance to a standard therapy known as CDK4/6 inhibitors, UT Southwestern Medical Center […]
A nationwide survey of people who were pregnant or trying to become pregnant has found that overall, 54% expressed interest in the RSV vaccine during pregnancy. Perceiving RSV as a serious illness in infants was the strongest predictor of likely vaccination during pregnancy. Likelihood to receive the RSV vaccine during pregnancy was also higher among […]
Depression and cardiovascular disease (CVD) are serious concerns for public health. Approximately 280 million people worldwide have depression, while 620 million people have CVD. It has been known since the 1990s that the two diseases are somehow related. For example, people with depression run a greater risk of CVD, while effective early treatment for depression […]
British pharmaceutical giant AstraZeneca on Thursday said net profit jumped 21 percent in the first three months of the year thanks to strong growth in sales of cancer drugs. Profit after tax climbed more than one fifth compared with the first quarter last year to $2.18 billion, AstraZeneca said in a results statement. “AstraZeneca had […]
Colorized transmission electron micrograph of Avian influenza A H5N1 viruses. Credit: Public Domain The discovery of traces of the bird flu virus in pasteurized cow milk in the United States sparked questions over whether the disease could spread to humans, but experts say there is little risk from food contamination. US authorities on Tuesday said […]
A pregnant woman stands for a portrait in Dallas, Thursday, May 18, 2023. According to provisional statistics for 2023 released by the Centers for Disease Control and Prevention on Thursday, April 25, 2024, U.S. births fell last year, in a substantial drop marking an apparent end to pandemic-related fluctuations and a return to a long-standing […]
Funmilayo Kotun, 66-years-old, a malaria patient is photographed in her one room in Makoko neighbourhood of Lagos, Nigeria, Saturday, April 20, 2024. When cases of locally transmitted malaria were found in the United States last year, it was a reminder that climate change is reviving the threat, or broadening the range, of some diseases. But […]
A nurse administers an injection to a malaria patient in a ward at Nightingale Medical Centre, in Kisumu, Kenya Tuesday, April. 16, 2024. Even after parts of Kenya participated in an important pilot of the world’s first malaria vaccine, with a reported drop in deaths for children under 5, the disease is still a significant […]
A new UCLA Health study has found that certain genetic variants could help explain how long-term pesticide exposure could increase the risk of Parkinson’s disease. While decades of research have linked pesticide exposure and Parkinson’s disease risk, researchers have sought to explain why some individuals with high exposure develop the disease while others do not. […]
Genomic surveillance can help control infectious diseases and antimicrobial resistance. Credit: Struelens et al/Frontiers The COVID-19 pandemic turned the world upside down. In fighting it, one of our most important weapons was genomic surveillance, based on whole genome sequencing, which collects all the genetic data of a given microorganism. This powerful technology tracked the spread […]
Women with heart disease are less often treated with cholesterol-lowering drugs than men, according to research presented today at ESC Preventive Cardiology 2024, a scientific congress of the European Society of Cardiology (ESC). “Cholesterol-lowering drugs save lives and prevent heart attacks, and should be prescribed to all patients with coronary artery disease,” said study author […]