Barrier’s deficiency impact in food allergy course in children

High TEWL was associated with a more severe disease course and a poor response to
treatment with antihistamines than in patients with less TEWL (r=,5, P.05). Faecal
calprotectin was elevated in 35/80 patients (43.7%) and was found to be significantly
higher in patients with more severe FA symptoms (P.05). Not all patients with positive
stool marker (45.7% 16/35) noticed unsteady stool in anamnesis. In addition, the most
effective influence on the severity of the TEWL had topical treatment with emollients,
than oral intake of the antihistamines (OR 13.5, 95% CI: 4.2-14.6; P.05).