Adding newly identified compound makes naloxone more potent, longer lasting, mouse study shows

Naloxone (orange) treats opioid overdose by kicking out opioids (pink) from the opioid receptor (teal). The newly discovered compound 368 (purple) strengthens the binding of naloxone to the opioid receptor, making it a more effective life-saving medicine. Credit: Emily Moskal/Stanford Medicine The ongoing opioid epidemic in the U.S. kills tens of thousands of people every year. Naloxone, sold under the brand name Narcan, has saved countless lives by reversing opioid overdoses. But new and more powerful opioids keep appearing, and first responders are finding it increasingly difficult to revive people Read More

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