Erk5 and its potential applications in cancer treatment

A new editorial paper was published in Oncoscience, titled “Role of Erk5 expressed in bone marrow mesenchymal stem cells on bone homeostasis and its potential applications in cancer treatment.” In their new editorial, researchers Tetsuhiro Horie and Eiichi Hinoi from Kanazawa Medical University, Gifu Pharmaceutical University, and Gifu University discuss Extracellular signal-regulated kinase 5 (Erk5). Erk5 belongs to the mitogen-activated protein kinase (MAPK) family and is specifically phosphorylated and subsequently activated by MAPK/Erk5 kinase 5 (Mek5). Compared to classical MAPKs Erk1/2, Erk5 is unique in that it has distinctive structures Read More

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