Summary of the evidence on potential neurogenesis-promoting and neuroinflammation-mitigating effects of oleacein. Credit: Cell Communication and Signaling (2024). DOI: 10.1186/s12964-024-01691-x Researchers are exploring natural compounds as potential alternatives to conventional antidepressants, which often yield inconsistent results. Compounds that activate the TrkB receptor are of particular interest, as this receptor stimulates the production of brain-derived neurotrophic factor (BDNF), a molecule believed to play a crucial role in preventing and treating neuroinflammation and depression. Due to its structural similarity to oleocanthal, a compound known for its anti-inflammatory properties, oleacein (OC) is considered Read More