Genetic atlas shows gum disease may be caused by immunosuppression of skin cells in the mouth

Gingival keratinocyte diversity is molecularly defined, spatially distinct, and preserved in vitro. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-49037-y Researchers have for the first time created an integrated single-cell RNA sequencing (scRNAseq) atlas of the human periodontium, the specialized tissues in the mouth that connect teeth to the underlying bone. This atlas will help identify the unique environments that impact on the development of gum disease (periodontitis), leading to better and more precise treatments. Millions of people worldwide experience gum disease (periodontitis). Aside from pain and tooth loss, this disease is Read More

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