Metformin and other antidiabetic drugs may help reduce the risk of dementia in patients with type 2 diabetes

Results show that the first-line antidiabetic drug metformin and the second-line sodium glucose co-transporter-2 (SGLT-2) inhibitors lower the risk of dementia and AD. Sulfonylureas significantly increased the risk in women. In patients aged 75 and over DPP4i, metformin, SGLT-2i and sulfonylureas increased the risk. Analysis includes stratification of patient-specific factors, including age, sex, comorbidity, BMI and baseline A1C. Credit: American Journal of Preventive Medicine Investigators analyzing the potential cognitive effects of antidiabetic medications in records of more than 1.5 million patients with type 2 diabetes mellitus (T2DM) found risks of Read More

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