Neurobiologists reveal secret of congenital central hypoventilation syndrome

Phox2b-expressing RTN neurons preferentially express Kcnq2 but not Kcnq3 channels. A Photomicrographs of coronal sections from the RTN, 7N, NTS, and LC show tdT-labeled Phox2b+ neurons (yellow) in the RTN express Kcnq2 transcript (cyan) but low Kcnq3 signal (magenta). B Summary of fluorescent in-situ hybridization results C Summary data plotted as mean ± maximum and minimum show the proportion of Phox2b-expressing cells per slice that express Kcnq2 transcript in the absence of Kcnq3. Credit: Nature Communications (2023). DOI: 10.1038/s41467-023-43834-7 In Greek mythology, a water nymph’s curse forces a man to Read More

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