Image of a neuron that was part of the dataset. Credit: Mount Sinai Health System Parkinson’s is associated with a higher risk of cognitive impairment and dementia that can severely impact quality of life. Cognitive symptoms include deficits in attention and mental flexibility, among others, and can pre-date the tremors and rigidity used to diagnose the disease. These and other cognitive abilities depend on the capacity of synapses to strengthen and weaken by dynamic addition or removal of neurotransmitter receptors within the synaptic membrane of relevant striatal and other neural Read More