Graphical abstract. Credit: Function (2024). DOI: 10.1093/function/zqae029 Obesity is a metabolic disorder tied to endothelial dysfunction and increased risk of cardiovascular disease. A recent study, published in the journal Function, investigated the mechanisms responsible for lipid transport and storage interaction with body fat and its impact on metabolic function. Single-cell RNA sequencing revealed enrichment of fatty acid-handling machinery in blood vessels and endothelial cells from mice that were fed a high-fat diet, indicating their specialized role in lipid metabolism. Phosphorylation of the gap junction protein called Connexin 43, which is Read More