Superimposed structures of the SRA domain bound to DNA double helix (orange) from the 3CLZ.pdb, modeled CMFT bound SRA (yellow) and methylated cytosine (green). Credit: Journal of Biological Chemistry (2024). DOI: 10.1016/j.jbc.2024.107443 In a new study, Yale researchers identified a molecule that binds to a disease-associated macrophage migration inhibitory factor (MIF) gene variant. The discovery, they say, could lead to the development of a new generation of precision medicine-based therapies that address diverse autoimmune and inflammatory conditions. The findings were published in the Journal of Biological Chemistry. Many autoimmune and Read More