Researchers uncover mechanism that fuels growth of aggressive B-cell lymphoma

A microscopic image of lymphoma tissue where the KLHL6 protein, coloured green, is mutated. The cells express the violet-coloured B-cell receptor on their surface. Credit: Leo Meriranta Researchers from the University of Helsinki and HUS investigated the effects of recurring mutations in the KLHL6 gene in diffuse large B-cell lymphoma, the most common cancer of the lymphatic system. The KLHL6 protein is part of a cellular system tasked with disposing of excess and unnecessary proteins. In many cancers, this system is disrupted, which advances malignant growth. The researchers found that Read More

Leave a Reply

Your email address will not be published. Required fields are marked *