Signaling pathway in brain helps maintain balance in microglia, prevent cognitive deficit

A 3D rendered confocal image shows a single TGF- ?1 knockout microglia being activated while it is surrounded by normal microglia that do not have the gene deletion. Credit: Agnes (Yu) Luo A new study led by University of Cincinnati researchers sheds new light on the role of a signaling pathway in the brain to maintain health and prevent inflammation and cognitive deficits. UC’s Agnes (Yu) Luo, Ph.D., is corresponding author on the research, published in the journal Nature Communications, and focused on a signaling pathway called TGF-? that plays Read More

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