The largest repository of transcription factor binding data in human tissues compiled to date

Credit: Loupe et al. (Nature Neuroscience, 2024). Transcription factors (TFs) are proteins that bind to specific DNA sequences, regulating the transcription of genetic information from DNA to messenger RNA (mRNA). These proteins play a pivotal role in the regulation of gene expression, which in turn impacts a wide range of biological processes and brain functions. While TFs have been the topic of numerous research studies, their binding dynamics in human tissue remain poorly understood. Shedding light on these binding dynamics could help to better understand how the expression of different Read More

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