Image of Piezo2 gene expression (shown in magenta) in lumbar dorsal root ganglion sections from mice. Credit: Lewin Lab of the Max Delbrück Center A team of researchers led by Oscar Sánchez-Carranza in Professor Gary Lewin’s lab at the Max Delbrück Center have identified a new function for the PIEZO2 protein—in mediating chronic pain hypersensitivity. The research suggests a new target for analgesics and potentially explains why pain medications that target voltage gated sodium channels have been disappointing as clinical targets. The study was published in the journal Brain. “There’s Read More
