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Aside from providing oxygen and nutrients to the tumor, blood vessels also secrete angiocrine factors. This study revealed that the factor Sfrp1, produced by vascular endothelial cells, plays an essential role in tumor growth by maintaining populations of cancer stem cells and regulating the Wnt signaling pathway. Credit: Hiroyasu Kidoya, University of Fukui Cancer is Read More
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by KeAi Communications Co. This schematic illustrates the observation of extensive activation of immune genes and transposable elements (TEs) in mice with EAM. Credit: Sixing Chen Regarded historically as genomic parasites, transposable elements (TEs) have now been recognized as significant contributors to cellular identity and function, especially in immune regulation. Mammalian genomes contain a vast Read More
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Inflammation is increased in old mice after NME. Credit: Nature Aging (2024). DOI: 10.1038/s43587-024-00620-4 Published in Nature Aging, University of Minnesota Medical School researchers have provided new insight into enhancing immune responses in older individuals and the potential for using immunotherapy to make older adults less vulnerable to infections. Using preclinical models, the research team Read More
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Hospitalization and homelessness—a Canadian snapshot. Credit: Canadian Institute of Health Information Nearly 30,000 people last year were homeless when admitted to hospital and/or discharged from hospital, a first-of-its-kind Canadian analysis shows. Almost all of these inpatients were admitted following a visit to an emergency department, and the complexity of their illnesses meant they stayed twice Read More
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Spending time in nature is good for us. Studies have shown that contact with nature can lift our well-being by affecting emotions, influencing thoughts, reducing stress and improving physical health. Even brief exposure to nature can help. One well-known study found that hospital patients recovered faster if their room included a window view of a Read More
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Two genes of the germline are essential for the development of brain tumours in Drosophila. Credit: IRB Barcelona Every cell in an organism carries an identical set of genetic instructions within its DNA. However, what determines whether a cell develops as a neuron, a muscle, or any other specific cell type lies in the activation Read More
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Training with the go4cognition tool. Credit: Assunta Jaeger Solving a quiz as a group while moving around the room at the same time—this combination is the basis of a new tool designed to prevent dementia. Researchers developed and evaluated it in the “go4cognition” project with industry partners and brought it to market maturity. Vanessa Lissek and Read More
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Motor impairment following brain injury has long been thought to be purely anatomical, and that traumatic brain injury, stroke or other neurological injury results in abnormal muscle tightness and rigidity. Evidence of this belief is based on studies of people recovering from stroke and multiple animal brain injury models. However, a recent research article challenges Read More
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Motor impairment following brain injury has long been thought to be purely anatomical, and that traumatic brain injury, stroke or other neurological injury results in abnormal muscle tightness and rigidity. Evidence of this belief is based on studies of people recovering from stroke and multiple animal brain injury models. However, a recent research article challenges Read More
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A new study led by researchers at University Hospitals Connor Whole Health has found that adults initially receiving chiropractic spinal manipulation for newly diagnosed radicular low back pain (sciatica) were significantly less likely to be prescribed tramadol over the following year compared to those receiving usual medical care. Tramadol is a synthetic opioid that has Read More
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Job loss and health decline of immigrant men in Germany. Credit: Max Planck Society A recent study by Silvia Loi and colleagues examines how life events like job loss and divorce affect the health of immigrants using data from the German Socio-Economic Panel. They find that immigrants experience more rapid declines in health as they Read More
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After a heart attack, foreign-born people are less likely to attend a relapse-preventing Heart School than native-born patients. But with access to a professional interpreter, participation increases. This was found in a study led by researchers at Linköping University, published in the journal IJC Heart & Vasculature, titled “Provision of professional interpreters and Heart School Read More
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University of New Mexico researchers have detected significant concentrations of microplastics in the testicular tissue of both humans and dogs, adding to growing concern about their possible effect on human reproductive health. In a new paper published in the journal Toxicological Sciences, a team led by Xiaozhong “John” Yu, MD, Ph.D., MPH, a professor in Read More
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Molecular tests and other screening tools can lessen the risk of potentially fatal reactions to antiseizure medications that millions of Americans take for epilepsy and other conditions, but skin rashes still require speedy medical attention, according to research from Rutgers Health. Rashes are a common side effect of antiseizure medications, occurring in 2 percent to Read More
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While 20% of California adults said they had four or more adverse childhood experiences, nearly 40% of that group reported an unmet mental health need in the last year, according to a new study by the UCLA Center for Health Policy Research. Adverse childhood experiences referred to physical or emotional neglect; physical, sexual and emotional Read More
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Double-diamond visualization of optimal patient involvement in the clinical decision-making process. Credit: Proceedings of the CHI Conference on Human Factors in Computing Systems (2024). DOI: 10.1145/3613904.3642353 Artificial intelligence has the potential to help older adults with cancer communicate with their doctors and participate more fully in decisions about their treatment, according to new Cornell research. Read More
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Records from nearly 30,000 nursing home residents indicate that blood pressure medications more than double the risk of life-threatening bone fractures, according to Rutgers Health research. The authors of the study, which appears in JAMA Internal Medicine, said the increased risk stems from the medications’ tendency to impair balance, particularly when patients first stand up Read More
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May is National Trauma Awareness Month. It’s a time to spread awareness about injury prevention and trauma. Falls are the No. 1 cause of nonfatal injuries among children up to 14 years old in the U.S., according to the National Institutes of Health. Many of these pediatric falls happen at home or on the playground. Read More
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Credit: SHVETS production from Pexels Growing a healthy baby relies on getting enough nutrients while pregnant. But rather than following a healthy diet to provide those nutrients, we’re concerned too many people are relying on “pink” multivitamins. These supplements are widely promoted for people who are pregnant or breastfeeding, and those who are planning to Read More
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Genetic factors are a small but significant contributor to severe depression that does not respond to standard therapy, according to researchers at Vanderbilt University Medical Center and Massachusetts General Hospital. The heritability of treatment-resistant depression (TRD) was found to have significant genetic overlap with schizophrenia, attention deficit disorder, cognitive, alcohol and smoking traits, and body Read More
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The onset of the COVID-19 pandemic changed how nearly everyone mediated their social interactions through technology. Some moved happy hours into video chats. Others delved deeper into social media, or took a step back from it. Millions of people worked or learned through computers. University of Washington researchers took particular interest in how this tech Read More
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A recent study published in Osteoporosis International sheds new light on the relationship between body mass index (BMI) trajectories during middle adulthood and the risk of bone fractures in late adulthood. The study, titled “Association of bone fracture with 30-year body mass index (BMI) trajectories: findings from the Framingham Heart Study,” provides valuable insights into Read More
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Bariatric surgery is associated with a reduced risk of breast cancer in women with obesity. These are the findings of a study conducted at the University of Gothenburg. The risk reduction is greatest for those with high blood insulin levels at the time of surgery. The study, published in JAMA Surgery, is based on data Read More
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A container of Narcan, a brand name version of the opioid overdose-reversal drug naloxone, sits on a table following a demonstration at the Health and Human Services Humphrey Building on Friday, Sept. 8, 2023, in Washington. The number of U.S. fatal overdoses fell in 2023 — for only the second time since the current national Read More
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Compared with pre-surgical (neoadjuvant) chemotherapy alone, adding perioperative immunotherapy—given before and after surgery—significantly improved event-free survival (EFS) in patients with resectable early-stage non-small cell lung cancer(NSCLC), according to researchers from The University of Texas MD Anderson Cancer Center. Results from the Phase III CheckMate 77T study were published today in the New England Journal of Read More
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Representations of the eight PTCs derived with NMF. Each PTC (one per row) indicates regions where FTP signal covaries across the dataset. Within each PTC, hotter regions (yellow/orange) indicate regions of stronger correlated FTP change. PTCs were estimated in the discovery cohort (ADNI-ADS). FTP, flortaucipir; NMF, non-negative matrix factorization; PTC, Pattern of Tau Covariance. Credit: Read More
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Researchers have found that 54% of older Native Americans have cognitive impairment, including 10% with dementia, highlighting a significant disparity with the rates of cognitive impairment and dementia in the general American population. The study also identified vascular injury, which can result from untreated hypertension and diabetes, and Alzheimer’s disease as equally responsible contributors to Read More
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Transgenic C. elegans worms expressing a green fluorescent reporter protein in the pharynx. The digestive system, visible in blue, extends along the entire length of the worm’s body. Credit: Bar-Ilan University Researchers from Bar-Ilan University, in collaboration with Sheba Medical Center, have developed a novel platform to model human muscle diseases in the C. elegans Read More
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Climate change, and its effects on weather patterns and adverse weather events, is likely to negatively affect the health of people with brain conditions, argues a UCL-led team of researchers. In a Personal View article, published in The Lancet Neurology, the team emphasizes the urgent need to understand the impact of climate change on people Read More
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This undated photo shows 6-month-old Nyla Brooke Haywood, a baby girl born Nov. 17, 2023, at Silver Cross Hospital in New Lenox, Illinois. Nyla was born at just 22 weeks weighing 1 pound and 1 ounce, making her what’s known as a “micropreemie.” She left Silver Cross Hospital on Monday weighing a healthy 10 pounds, Read More
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