Building a blueprint of metabolic health—from mouse to human

Graphical abstract. Credit: Cell Systems (2024). DOI: 10.1016/j.cels.2024.05.006 Metabolic syndrome (MetS) is a health condition characterized by a group of risk factors: high blood pressure, high blood sugar, unhealthy cholesterol levels, and abdominal fat. These factors increase the risk of heart disease, type 2 diabetes, and other serious health problems. Previous studies have shown that both genetics and lifestyle influence MetS. But human studies have found it challenging to pinpoint the disease’s exact genetic factors and how they interact with our environment—the differences between people’s diets and lifestyles have proven Read More

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