Left, malar rash in a (huNSGW41-derived) Lupus THX mouse (three weeks after pristane injection). Middle, serum antinuclear IgGs (scale bar, 20??m) and kidney immunopathology (H&E and anti-huIgG immunofluorescence; scale bar, 100??m) in Lupus THX and THX mice (12 weeks after pristane or PBS injection). Credit: Nature Immunology (2024). DOI: 10.1038/s41590-024-01880-3 A breakthrough for biomedical research promises new insight into immunotherapy development and disease modeling. Scientists at The University of Texas Health Science Center at San Antonio have created a humanized mouse model with a human immune system and a human-like Read More