The different versions of the signal molecule PGC-1? react to different stimuli. The standard version (“a”) is produced in response to long-term exercise, whereas the alternative versions (“b/c”) are produced in response to short-term exercise or cold exposure. A lack of these versions makes it harder for affected individuals to respond to these stimuli by burning fat or building muscle mass. Credit: K. Nomura et al. Published by Elsevier GmbH. DOI: 10.1016/j.molmet.2024.101968 Some people lose weight slower than others after workouts, and a Kobe University research team found a reason. Read More